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J2000

Sigma-Aldrich

C16-Juvenilhormon

≥65%, liquid, non-sterile

Synonym(e):

JH-III, Juveniles Hormon III, Manduca Hormon, trans,trans-10,11-Epoxy-3,7,11-trimethyl-2,6-dodecadiensäure-methylester

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About This Item

Empirische Formel (Hill-System):
C16H26O3
CAS-Nummer:
24198-95-6
Molekulargewicht:
266.38
Beilstein:
1316317
EG-Nummer:
246-072-9
MDL-Nummer:
MFCD00135990
UNSPSC-Code:
51111800
PubChem Substanz-ID:
24896191
NACRES:
NA.32

Biologische Quelle

synthetic (organic)

Qualitätsniveau

200

Sterilität

non-sterile

Form

liquid

Konzentration

≥65%

Methode(n)

activity assay: suitable

Versandbedingung

ambient

Lagertemp.

−20°C

SMILES String

COC(=O)\C=C(/C)CC\C=C(/C)CC[C@H]1OC1(C)C

InChI

1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+

InChIKey

QVJMXSGZTCGLHZ-ZPLWXOMKSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Research Area: Cell Signaling

Juvenile hormone III (JH III) is the most prevalent juvenile hormone (JH) found in insects.

Anwendung

Juvenile hormone III has been used to:
  • study the effect of juvenile hormone on mictic (sexual) female production of the rotifer Brachionus plicatilis Muller
  • study the effect of juvenile hormone on head GB19811 (putative Takeout/juvenile hormone binding protein) mRNA levels in adult honeybees
  • study the effect of juvenile hormone on gonadotropic and physiological functions in bumblebee Bombus terrestris

Biochem./physiol. Wirkung

JHBPs (JH-binding proteins) protect JH (juvenile hormone) from JH esterase- and epoxide hydrolase-mediated degradation. They also help in delivering JH to target tissues.Juvenile hormones(JHs) are a group of acyclic sesquiterpenoids, and in some insect lineages, the farnesol backbone of these compounds undergoes chemical modification to produce a homologous series of hormones. JH is essential for insect development and reproduction in every aspect. It plays a key role in metamorphosis and caste determination in social insects. It modulates behavior, polyphenism, larval and adult diapause, and ovarian development. The sesquiterpenoid backbone of juvenile hormone III (JH III) is biosynthesized through the classical mevalonate (MVA) pathway in cockroaches.
Controls the larval metamorphosis of insects, including the retention of juvenile characteristics.

Inhibitor

Produkt-Nr.
Beschreibung
Preisangaben

A9554

Allatostatin IV, ≥97% (HPLC)

SML2609

JH-I-25, ≥98% (HPLC)

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

H-Sätze

H413

Gefahreneinstufungen

Aquatic Chronic 4

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

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A Ishikawa et al.
Insect molecular biology, 21(1), 49-60 (2011-10-13)
Most aphids show reproductive polyphenism, i.e. they alternate their reproductive modes from parthenogenesis to sexual reproduction in response to short photoperiods. Although juvenile hormone (JH) has been considered a likely candidate for regulating the transition from asexual to sexual reproduction
Shuang Guo et al.
PLoS genetics, 17(2), e1009352-e1009352 (2021-02-03)
Diapause, a programmed developmental arrest primarily induced by seasonal environmental changes, is very common in the animal kingdom, and found in vertebrates and invertebrates alike. Diapause provides an adaptive advantage to animals, as it increases the odds of surviving adverse
Cheolho Sim et al.
Insect molecular biology, 22(1), 1-11 (2012-11-06)
Juvenile hormone (JH) controls diverse physiological and developmental events including diapause and nutrient metabolism. The focal point of endocrine regulation in adult reproductive diapause is initiated by a halt of JH synthesis. In diapausing females of the mosquito Culex pipiens
Gallardo et al.
Journal of experimental marine biology and ecology, 252(1), 97-107 (2000-08-30)
Juvenile hormone (JH) and serotonin (5-HT) were previously shown to enhance mictic (sexual) female production of the rotifer Brachionus plicatilis in batch cultures. To explore the basis of these effects, experiments were conducted on isolated individuals. JH treatment of maternal
Michael E Scharf et al.
Insect biochemistry and molecular biology, 35(3), 207-215 (2005-02-12)
Termites express polyphenism during caste differentiation that is mostly undefined at the molecular level. Using the eastern subterranean termite, Reticulitermes flavipes Kollar, we wanted (1) to test juvenile hormone (JH) model assays for their ability to induce detectable molecular changes
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