F0806

Factor IX human

aqueous glycerol solution, ≥145 units/mg protein

• Synonym(e): Christmas factor, Plasma thromboplastin component
• CAS-Nummer: 9001-28-9
• UNSPSC Code: 12352202
• NACRES: NA.61
• MDL number: MFCD00163303
• Form: aqueous glycerol solution
• Biological source: human
• Mol wt: 55 kDa

Eigenschaften

• biological source: human
• Quality Segment: 200
• form: aqueous glycerol solution
• specific activity: ≥145 units/mg protein
• mol wt: 55 kDa
• technique(s): ligand binding assay: suitable
• UniProt accession no.: P00740
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... F9(2158)

Beschreibung

General description

Factor IX is a 55 kDa single chain vitamin K-dependent plasma zymogen which plays a key role in the intrinsic and extrinsic blood coagulation systems.

Application

Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).

Physical form

Aqueous solution containing 50% (v/v) glycerol

Other Notes

One unit is equivalent to the Factor IX activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.

View this factors role in the Coagulation Cascade

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)