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Merck

D9190

Sigma-Aldrich

DCEBIO

≥98% (HPLC), solid

Synonym(e):

5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazole-2-one

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About This Item

Empirische Formel (Hill-System):
C9H8N2OCl2
CAS-Nummer:
Molekulargewicht:
231.08
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77

Assay

≥98% (HPLC)

Form

solid

Farbe

white to off-white

Löslichkeit

DMSO: >10 mg/mL

SMILES String

CCN1C(=O)Nc2cc(Cl)c(Cl)cc12

InChI

1S/C9H8Cl2N2O/c1-2-13-8-4-6(11)5(10)3-7(8)12-9(13)14/h3-4H,2H2,1H3,(H,12,14)

InChIKey

LKHRMULASXZCLG-UHFFFAOYSA-N

Biochem./physiol. Wirkung

DCEBIO facilitates Cl secretion in the epithelia by activating K+ and Cl currents.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Naoto Fujii et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 318(2), R390-R398 (2020-01-09)
Local skin heating to 42°C causes cutaneous thermal hyperemia largely via nitric oxide (NO) synthase (NOS)-related mechanisms. We assessed the hypothesis that ATP-sensitive K+ (KATP) channels interact with NOS to mediate cutaneous thermal hyperemia. In 13 young adults (6 women
Amy N Savitski et al.
Respiratory research, 10, 120-120 (2009-12-01)
Secondhand smoke (SHS) exposure is an independent risk factor for asthma, rhinosinusitis, and more severe respiratory tract infections in children and adults. Impaired mucociliary clearance with subsequent mucus retention contributes to the pathophysiology of each of these diseases, suggesting that
Jelena Sikimic et al.
Frontiers in endocrinology, 11, 545638-545638 (2020-11-17)
Congenital hyperinsulinism (CHI) is a rare disease characterized by persistent hypoglycemia as a result of inappropriate insulin secretion, which can lead to irreversible neurological defects in infants. Poor efficacy and strong adverse effects of the current medications impede successful treatment.
Hiroaki Kito et al.
American journal of physiology. Cell physiology, 319(2), C345-C358 (2020-06-11)
The maturity of osteoblasts by proliferation and differentiation in preosteoblasts is essential for maintaining bone homeostasis. The beneficial effects of vitamin D on bone homeostasis in mammals have been demonstrated experimentally and clinically. However, the direct actions of vitamin D

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