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C8261

Chenodesoxycholsäure Natriumsalz

≥97%

Synonym(e):

Chenodiol

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Über diesen Artikel

Empirische Formel (Hill-System):
C24H39NaO4
CAS-Nummer:
Molekulargewicht:
414.55
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
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description

anionic

Quality Segment

assay

≥97%

form

powder

mol wt

414.55 g/mol

technique(s)

protein purification: suitable

SMILES string

[Na].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])CC[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O4.Na.H/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);;/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;;/m1../s1

InChI key

WANBNZVOEKGHSS-VQNKLXGESA-N

General description

Sodium chenodeoxycholate is a bile salt, which has been shown to accelerate colonic transit and improve bowel function. [1]

Application

Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. [2] It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores. [3]

Biochem/physiol Actions

Bile Salt

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Dieser Artikel
30970C644527029
form

powder

form

powder

form

powder

form

powder

assay

≥97%

assay

≥98.0% (dry matter, NT)

assay

≥99%

assay

≥97.0% (dried material, NT)

technique(s)

protein purification: suitable

technique(s)

DNA purification: suitable, RNA purification: suitable, electrophoresis: suitable

technique(s)

-

technique(s)

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

description

anionic

description

anionic

description

anionic

description

anionic

mol wt

414.55 g/mol

mol wt

micellar avg mol wt 1200-5000

mol wt

micellar avg mol wt 900-1300

mol wt

micellar avg mol wt 900-1300


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



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Artikel

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.


Sarinya Tawthep et al.
Journal of bioscience and bioengineering, 124(5), 514-522 (2017-07-29)
Understanding the dynamics of secondary bile acid (SBA) formation in the gut by SBA-producing bacteria is important for host health, as SBAs have been shown to affect host pathophysiology and gut microbiota composition. However, our knowledge of SBA producers is
R L Kandell et al.
Nutrition and cancer, 16(3-4), 227-238 (1991-01-01)
Two bile salts, sodium chenodeoxycholate and sodium deoxycholate, induced a DNA repair response in the bacterium Escherichia coli. Similarly, a bile acid and a bile salt, chenodeoxycholic acid and sodium deoxycholate, induced DNA repair (indicated by unscheduled DNA synthesis) in
L J Wheeldon et al.
Journal of applied microbiology, 105(6), 2223-2230 (2009-01-06)
To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores. Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat or



Global Trade Item Number

SKUGTIN
C8261-500MG04061833619117
C8261-1G04061833521984

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