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O7139

Sigma-Aldrich

Monoclonal Anti-Oligodendrocyte Marker O4 antibody produced in mouse

clone O4, purified immunoglobulin, lyophilized powder

Synonyme(s) :

Oligodendrocyte Marker O4 Antibody

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

O4, monoclonal

Forme

lyophilized powder

Espèces réactives

mouse, rat, chicken, human

Technique(s)

flow cytometry: 0.25 μg/106 cells (rate differentiated cortical stem cells)
immunocytochemistry: 1-10 μg/mL

Isotype

IgM

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... OMG(4974)

Description générale

Monoclonal anti-oligodendrocyte marker O4 was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with white matter of the corpus callosum from bovine brain. Oligodendrocytes are myelinating cells in the central nervous system (CNS) that form the myelin sheath of axons to support rapid nerve conduction.

Immunogène

white matter of corpus callosum from bovine brain.

Application

Monoclonal anti-oligodendrocyte marker O4 antibody produced in mouse has been used in immunocytochemistry and immunofluorescence.

Actions biochimiques/physiologiques

Oligodendrocyte marker O4 functions as a development marker of oligodendrocytes. The monoclonal anti-oligodendrocyte marker O4 antibody has been used to describe a biologically distinct stage of the oligodendroglial lineage in-vitro.†

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Neuroglial Cells in Long-Term Primary Cultures from the Gilthead Seabream (Sparus Aurata L.): New Functional In Vitro Model from Bony Fish Brain
Centoducati G, et al.
Italian Journal of Animal Science, 12 (2013)
Oligodendrocytes: biology and pathology
Bradl M, et al.
Acta Neuropathologica, 119, 37-53 (2010)
An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells.
Niu J, et al.
Journal of Neuroscience Methods, 209, 241-249 (2012)
SDF-1a Secreted by Human CD133-Derived Multipotent Stromal Cells Promotes Neural Progenitor Cell Survival Through CXCR7
Benjamin Bakondi
Stem Cells and Development (2011)
Jichao Yuan et al.
Oncotarget, 8(12), 19855-19865 (2017-04-21)
Neural stem/progenitor cells (NSPCs) are an important source of cells for cell replacement therapy after nerve injury. How to induce NSPCs differentiation towards neurons and oligodendrocytes is a challenging issue in neuroscience research. In the present study, we polarized microglia

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