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HPA015705

Anti-ZNF330 antibody produced in rabbit

Name: Anti-ZNF330 antibody produced in rabbit
Brand: SIGMA
Price: 881 CAD

Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-Nucleolar autoantigen 36, Anti-Nucleolar cysteine-rich protein, Anti-Zinc finger protein 330

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Conditionnement	Référence	Disponibilité	Prix
100 μL		Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.	881,00 $

A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.43

Human Protein Atlas Number:

HPA015705

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC

Citations:

881,00 $

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

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Enhanced Validation Antibodies

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Cet article	HPA043696	HPA027309	HPA030912
Sigma-Aldrich HPA015705 Anti-ZNF330 antibody produced in rabbit	Sigma-Aldrich HPA043696 Anti-ZNF320 antibody produced in rabbit	Sigma-Aldrich HPA027309 Anti-ZNF232 antibody produced in rabbit	Sigma-Aldrich HPA030912 Anti-ZNF843 antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal

Immunogen

Zinc finger protein 330 recombinant protein epitope signature tag (PrEST)

Application

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies^® protocols and other useful information.

Biochem/physiol Actions

Zinc finger protein 330 is a protein encoded by the ZNF330 gene in humans and is mapped to chromosome 4q31.1-->q31.2. It is found to be localized in the nucleolus and mitochondria of mammalian cells, due to its nucleolar localization signal (NoLS) that is highly-conserved.[1] This protein is highly conserved and consists of cystein-rich domain. During apoptosis induction, it is translocated from mitochondria to the cytoplasm and helps in releasing cytochrome c.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Other Notes

Corresponding Antigen APREST72583

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificats d'analyse (COA)

Lot/Batch Number

R05984

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NOA36 protein contains a highly conserved nucleolar localization signal capable of directing functional proteins to the nucleolus, in mammalian cells.

Ivan S de Melo et al.

PloS one, 8(3), e59065-e59065 (2013-03-22)

NOA36/ZNF330 is an evolutionarily well-preserved protein present in the nucleolus and mitochondria of mammalian cells. We have previously reported that the pro-apoptotic activity of this protein is mediated by a characteristic cysteine-rich domain. We now demonstrate that the nucleolar localization

Genomic structure and chromosome location of the human gene encoding the zinc finger autoantigen ZNF330.

J Bolívar et al.

Cytogenetics and cell genetics, 93(3-4), 234-238 (2001-08-31)

We have recently described a novel zinc finger cDNA, ZNF330, which was immunologically characterized as a new human autoantigen, highly conserved during evolution from nematodes to humans. The protein was found at the nucleolus and the cytoplasm in interphase and

NOA36/ZNF330 is a conserved cystein-rich protein with proapoptotic activity in human cells.

Ivan S de Melo et al.

Biochimica et biophysica acta, 1793(12), 1876-1885 (2009-11-10)

Translocations of regulator proteins from or to the mitochondria are key events in apoptosis regulation. NOA36/ZNF330 is a highly evolutionary conserved protein with a characteristic cystein-rich domain. In this work we address its mitochondrial localization and we demonstrate that a

Numéro d'article de commerce international

Référence	GTIN
HPA015705-100UL	04061835681044
HPA015705-25UL	04061842805433

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