M1629

Medroxyprogesterone 17-acetate

synthetic (organic), ≥97% (HPLC), synthetic progestogen, powder

• Synonyme(s) : 17α-Acetoxy-6α-methylprogesterone, 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate, 6α-Methyl-17α-acetoxyprogesterone, 6α-Methyl-17α-hydroxyprogesterone acetate
• Formule empirique (notation de Hill) : C₂₄H₃₄O₄
• Numéro CAS: 71-58-9
• Poids moléculaire : 386.52
• NACRES: NA.77
• PubChem Substance ID: 24896674
• UNSPSC Code: 12352200
• EC Number: 200-757-9
• MDL number: MFCD00010483
• Beilstein/REAXYS Number: 2066112
• Assay: ≥97% (HPLC)
• Form: powder

Propriétés

• Nom du produit: Medroxyprogesterone 17-acetate, ≥97% (HPLC)
• biological source: synthetic (organic)
• Quality Segment: 100
• sterility: non-sterile
• assay: ≥97% (HPLC)
• form: powder
• mp: 206-207 °C (lit.)
• solubility: chloroform: 350 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
• InChI: 1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
• InChI key: PSGAAPLEWMOORI-PEINSRQWSA-N
• Gene Information: human ... AR(367), ESR1(2099), ESRRA(2101), NR3C1(2908), NR3C2(4306), PGR(5241) ; rat ... Ar(24208)

Description

Biochem/physiol Actions

Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• pictograms: GHS08
• signalword: Warning
• hcodes: H351,H413
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 4 - Carc. 2
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges