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E0789

Casein, Hammarsten bovine

Synonyme(s) :

Casein from bovine milk

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ConditionnementRéférenceDisponibilitéPrix
500 g
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315,00 $
5 kg
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A propos de cet article

Numéro CAS:
UNSPSC Code:
12352202
NACRES:
NA.61
EC Number:
232-555-1
MDL number:
Form:
powder
Assay:
>90% dry basis
Biological source:
bovine milk (Hammarsten)

315,00 $


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biological source

bovine milk (Hammarsten)

Quality Level

assay

>90% dry basis

form

powder

technique(s)

enzyme immunoassay: suitable

mp

280 °C (dec.) (lit.)

UniProt accession no.

storage temp.

room temp

SMILES string

[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

InChI key

BECPQYXYKAMYBN-UHFFFAOYSA-N

General description

Casein is an amphiphilic protein.
Casein, a phosphoprotein, is the principal protein component of milk which is almost entirely expressed in the lactating mammary gland.[1] In bovine milk they are classified according to their calcium sensitivity: αs1-, αs2-, and β-caseins precipitate in the presence of calcium; whereas κ-casein remains in solution. [2]

Application

Casein, Hammarsten bovine has been used as a substrate for Aplysia californica calpain to study its activity.[3]
The product is useful as a protease substrate.

Biochem/physiol Actions

Casein is useful in food industries and non-food applications. It has the property for emulsification, foam formation, and stabilization, water-binding, and gelation. Casein is also considered heat and acid-stable.
Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.


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Consulter la Bibliothèque de documents



Margaret H Hastings et al.
PloS one, 12(10), e0186646-e0186646 (2017-10-21)
Calpains are a family of intracellular proteases defined by a conserved protease domain. In the marine mollusk Aplysia californica, calpains are important for the induction of long-term synaptic plasticity and memory, at least in part by cleaving protein kinase Cs
Krisztina Nagy et al.
The Journal of biological chemistry, 285(50), 38811-38817 (2010-10-06)
The possible mechanism of casein aggregation and micelle buildup was studied in a new approach by letting α-casein adsorb from low concentration (0.1 mg·ml(-1)) solutions onto the charged surfaces of polyelectrolyte films. It was found that α-casein could adsorb onto
Andreas F Kolb et al.
PloS one, 6(7), e21775-e21775 (2011-07-27)
The major physiological function of milk is the transport of amino acids, carbohydrates, lipids and minerals to mammalian offspring. Caseins, the major milk proteins, are secreted in the form of a micelle consisting of protein and calcium-phosphate.We have analysed the



Numéro d'article de commerce international

RéférenceGTIN
E0789-500G04061833601266
E0789-5KG04061833619735

Questions

  1. 製薬会社で医薬品の品質試験を行なっている者です。このカゼイン(Hammerstein)において、日局等の公定書に基づいて赤外吸収スペクトル測定法の臭化カリウム錠剤法の試験を実施した実績がありますでしょうか。もしなければ、実施実績のある他のカゼイン(Hammerstein)製品の取扱いはございますでしょうか。ご回答お願いいたします。

    1 answer
    1. There are currently two Hammerstein versions of Casein available, E0789 and 1.02242. Neither of these products are tested according to the JP.

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