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P1499

紫檀芪

≥97% (HPLC), apoptosis inducer, solid

别名:

紫檀, 3,5-二甲氧基-4′-羟基茋, 4-[(1E)-2-(3,5-二甲氧基苯基)乙烯基] 苯酚

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10 mg

即日发货发货地SIGMA ALDRICH Pte Ltd

$422.00

关于此项目

经验公式(希尔记法):
C16H16O3
化学文摘社编号:
分子量:
256.30
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
protect from light

$422.00


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产品名称

紫檀芪, ≥97% (HPLC), solid

Quality Segment

assay

≥97% (HPLC)

form

solid

storage condition

protect from light

solubility

DMSO: >20 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

COc1cc(OC)cc(\C=C\c2ccc(O)cc2)c1

InChI

1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+

InChI key

VLEUZFDZJKSGMX-ONEGZZNKSA-N

General description

紫檀芪(反式-3,5-二甲氧基-4-羟基芪)抗氧化剂是白藜芦醇的类似物,存在于蓝莓、树木和几种葡萄中。[1]

Application

紫檀芪已用于:
  • 研究其抗氧化应激活性以及在核转录因子E2相关因子2(Nrf2)-抗氧化反应元件(ARE)信号转导通路中的调节作用
  • 确定其对激素耐受性乳腺癌细胞雌激素受体α(ERα)转录激活的影响
  • 通过MTT(3-[4,5-二甲基噻唑-2-基]-2,5二苯基四氮唑溴化物)活力检测法研究其对人表皮样癌细胞(A-431)中2-氯乙基乙基硫醚(CEES)的细胞毒性的影响。

Biochem/physiol Actions

抗氧化、抗增殖、细胞凋亡诱导、抗高血糖、抗糖尿病。
紫檀芪对几种恶性肿瘤具有抗癌作用,因此可作为活性抗癌药物。在雌激素受体阳性和阴性乳腺癌细胞系中,它可激活细胞凋亡并抑制细胞活性。[1]

Disclaimer

空气敏感性

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此商品
SML1078SML1787D6571
assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

DMSO: >20 mg/mL, H2O: insoluble

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 3 mg/mL, clear (warmed)

solubility

DMSO: ≥20 mg/mL

storage condition

protect from light

storage condition

protect from light

storage condition

-

storage condition

-


pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
P1499-10MG04061834355113

Questions

  1. Actually we are using as a Analytical Standard for HPLC assay of Pterostilbene in RM and Final Product .Can we use this? if we can use How much purity we have to take for Calculation

    1 answer
    1. This product is tested for suitability in HPLC. The minimum purity of this material is 97%, and the maximum water content is 2.0 mol. These values are lot-specific and reported in the Certificate of Analysis. This material is not tested for use as an analytical standard. Suitability for this application would have to be determined by the end user. Please see the link below to review a sample or lot specific Certificate:
      https://www.sigmaaldrich.com/product/sigma/p1499#product-documentation

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