29208

(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide

for protein sequence analysis (by MALDI-MS), ≥98.5%

• Szinonimák: N-Succinimidyl [tris(2,4,6-trimethoxyphenyl)phosphonio]acetate bromide, TMPP-Ac-OSu
• Tapasztalati képlet (Hill-képlet): C₃₃H₃₉BrNO₁₃P
• CAS-szám: 226409-58-1
• Molekulatömeg: 768.54
• MDL-szám: MFCD03095505
• UNSPSC kód: 41116105
• PubChem Substance ID: 329753320
• NACRES: NA.21
• Teszt: ≥98.5% (HPLC); ≥98.5%

Tulajdonságok

• grade: for protein sequence analysis (by MALDI-MS)
• Minőségi szint: 100
• Teszt: ≥98.5% (HPLC); ≥98.5%
• technika/technikák: MALDI-MS: suitable
• mp: 199-205 °C (dec.)
• tárolási hőmérséklet: −20°C
• SMILES string: [Br-].COc1cc(OC)c(c(OC)c1)[P+](CC(=O)ON2C(=O)CCC2=O)(c3c(OC)cc(OC)cc3OC)c4c(OC)cc(OC)cc4OC
• InChI: 1S/C33H39NO13P.BrH/c1-38-19-12-22(41-4)31(23(13-19)42-5)48(18-30(37)47-34-28(35)10-11-29(34)36,32-24(43-6)14-20(39-2)15-25(32)44-7)33-26(45-8)16-21(40-3)17-27(33)46-9;/h12-17H,10-11,18H2,1-9H3;1H/q+1;/p-1
• Nemzetközi kémiai azonosító kulcs: YKMSQZIYVKTUHI-UHFFFAOYSA-M

Leírás

Általános leírás

N-Succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP-Ac-OSu) is an acylating reagent, and is generally used for the selective derivatization of N-terminal a-amino group of peptide. The TMPP-acetylated peptides undergo fragmentation thereby creating a-type ions, thus obtaining sequence information becomes easier, even without the usage of automated computational approach. It can be used as a labelling reagent in liquid chromatography-coupled mass spectrometry (LC-MS/MS) of N-terminal peptides, so as to improve ionization efficiency, simplify fragmentation, and retention times, thereby leading to better separation of peptides.

Alkalmazás

TMPP-Ac-OSu was used for labelling peptides, in tandem mass spectrometry, done for converting arginine to ornithine, in order to improve the fragmentation pattern of peptides.

Kiszerelés

Bottomless glass bottle. Contents are inside inserted fused cone.

Egyéb megjegyzések

Reagent for modifying N-termial of peptides for fast atom bombardment, FAB or matrix assisted laser desorption/ionization MS, MALDI MS

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)