A7793
5-Aminolevulinic acid hydrochloride
BioReagent, suitable for cell culture, powder, ≥98%
Synonyme(s) :
δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
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A propos de cet article
Formule linéaire :
NH2CH2C(O)CH2CH2COOH · HCl
Numéro CAS:
Poids moléculaire :
167.59
UNSPSC Code:
12352209
NACRES:
NA.75
PubChem Substance ID:
EC Number:
226-679-5
Beilstein/REAXYS Number:
3690651
MDL number:
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BioReagent
Quality Level
assay
≥98%
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL
storage temp.
−20°C
SMILES string
Cl[H].NCC(=O)CCC(O)=O
InChI
1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
InChI key
ZLHFONARZHCSET-UHFFFAOYSA-N
Application
5-Aminolevulinic acid formed from glycine and succinyl CoA by ALA synthase is the first compound in prophyrin biosynthesis pathway. 5-Aminolevulinic acid is used in photodynamic therapy. This compound may be used to study the effects of photodynamic therapy in vitro.
Biochem/physiol Actions
Intermediate in heme biosynthesis.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenu apparenté
Firas Şueki et al.
Photodiagnosis and photodynamic therapy, 27, 95-99 (2019-05-18)
Photodynamic Therapy (PDT) is a promising antitumor and anti-bacterial treatment method for its high selectivity, non-invasiveness, and minimal side effects. However, cellular mechanisms may lead to PDT resistance and thus effect efficacy. The aim of this study is to test
J D Bastian et al.
Osteoarthritis and cartilage, 17(4), 539-546 (2008-10-08)
Outcome in osteochondral allografting is limited by the immunological incompatibility of the grafted tissue. Based on a resistance of chondrocytes to photodynamic therapy in cell culture it is proposed that 5-aminolevulinic acid-based photodynamic therapy (5-ALA-PDT) might be used to inactivate
Ruiqi Liao et al.
Cell reports, 31(13), 107832-107832 (2020-07-02)
Protein ensembles control genome function by establishing, maintaining, and deconstructing cell-type-specific chromosomal landscapes. A plethora of small molecules orchestrate cellular functions and therefore may link physiological processes with genome biology. The metabolic enzyme and hemoglobin cofactor heme induces proteolysis of
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| A7793-1G | 04061833386330 |
| A7793-10MG | 04061833386316 |
| A7793-500MG | 04061833386354 |