A3785

5-Aminolevulinic acid hydrochloride

≥98%, suitable for ligand binding assays

• Synonyme(s) : δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
• Formule linéaire : NH₂CH₂C(O)CH₂CH₂COOH · HCl
• Numéro CAS: 5451-09-2
• Poids moléculaire : 167.59
• Numéro Beilstein : 3690651
• Numéro CE : 226-679-5
• Numéro MDL: MFCD00012869
• Code UNSPSC : 12352209
• ID de substance PubChem : 24890811
• Nomenclature NACRES : NA.26

Propriétés

• product name: 5-Aminolevulinic acid hydrochloride, ≥98%
• Niveau de qualité: 300
• Pureté: ≥98%
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Pf: 150 °C
• Température de stockage: −20°C
• Chaîne SMILES: Cl[H].NCC(=O)CCC(O)=O
• InChI: 1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
• Clé InChI: ZLHFONARZHCSET-UHFFFAOYSA-N

Description

Application

5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy for A431 tumor bearing mice.

Actions biochimiques/physiologiques

5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget′s disease and HPV infection-associated cervical condylomata acuminata.

Intermediate in heme biosynthesis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable