72335
9-(2,2-Dicyanovinyl)julolidine
BioReagent, suitable for fluorescence, ≥97.0% (HPLC)
Synonyme(s) :
9-Julolidinylmethylenemalononitrile, DCVJ
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A propos de cet article
Formule empirique (notation de Hill) :
C16H15N3
Numéro CAS:
Poids moléculaire :
249.31
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
413882
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BioReagent
Quality Segment
assay
≥97.0% (HPLC)
form
crystals
solubility
DMSO: soluble, chloroform: soluble
fluorescence
λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol
suitability
suitable for fluorescence
SMILES string
N#C\C(=C/c1cc2CCCN3CCCc(c1)c23)C#N
InChI
1S/C16H15N3/c17-10-13(11-18)7-12-8-14-3-1-5-19-6-2-4-15(9-12)16(14)19/h7-9H,1-6H2
InChI key
LROAUBRDKLVBCP-UHFFFAOYSA-N
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Fluorescent probe for binding to proteins etc., quantum yield increases by decreasing free rotation; abs at ~450 nm, em at 480-505 nm (solvent dep.)
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Fluid shear stress increases membrane fluidity in endothelial cells: a study with DCVJ fluorescence.
M A Haidekker et al.
American journal of physiology. Heart and circulatory physiology, 278(4), H1401-H1406 (2000-04-06)
Fluid shear stress (FSS) has been shown to be an ubiquitous stimulator of mammalian cell metabolism. Although many of the intracellular signal transduction pathways have been characterized, the primary mechanoreceptor for FSS remains unknown. One hypothesis is that the cytoplasmic
A Bhattacharyya et al.
Indian journal of biochemistry & biophysics, 32(6), 442-446 (1995-12-01)
Di(cyano vinyl)julolidine (DCVJ) is a fluorescent probe which has been used to monitor the local mobility of its binding sites on proteins. It shows a concentration dependence of its emission spectrum in water. At higher DCVJ concentrations, a longer wavelength
Andrea Hawe et al.
Pharmaceutical research, 27(2), 314-326 (2009-12-31)
The aim was to evaluate fluorescent molecular rotors (DCVJ and CCVJ), which are mainly sensitive to viscosity, for the characterization of polysorbate-containing IgG formulations and compare them to the polarity-sensitive dyes ANS, Bis-ANS and Nile Red. IgG formulations with polysorbate
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 72335-5MG | 04061834370659 |