UC263
7-Hydroxycoumarin glucuronide sodium salt
Actin polymerization inhibitor, solid
Synonyme(s) :
7-Hydroxy-2H-1-benzopyran-2-one glucuronide sodium salt, Umbelliferone glucuronide sodium salt
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A propos de cet article
Formule empirique (notation de Hill) :
C15H13NaO9
Numéro CAS:
Poids moléculaire :
360.25
UNSPSC Code:
12161501
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
solid
Nom du produit
7-Hydroxycoumarin glucuronide sodium salt,
form
solid
color
white to faint yellow
mp
≥285 °C
storage temp.
2-8°C
SMILES string
[Na+].O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C([O-])=O)Oc2ccc3C=CC(=O)Oc3c2
InChI
1S/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1
InChI key
SKHLGBDGEPDEME-KSOKONAESA-M
Application
7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxycoumarin metabolites.
Phase II (UDP-GT) metabolite of 7-hydroxycoumarin.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenu apparenté
Hanneke G M Wittgen et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(6), 1076-1079 (2012-03-15)
Coumarin (1,2-benzopyrone) is a natural compound that has been used as a fragrance in the food and perfume industry and could have therapeutic usefulness in the treatment of lymphedema and different types of cancer. Several previous pharmacokinetic studies of coumarin
The use of capillary electrophoresis for studying the in vitro glucuronidation of 7-hydroxycoumarin.
D P Bogan et al.
Journal of capillary electrophoresis, 2(5), 241-245 (1995-09-01)
An assay utilizing CE, has been developed for studying the in vitro metabolism of 7-hydroxycoumarin to 7-hydroxycoumarin-glucuronide. A reaction mixture containing a crude preparation of bovine uridine diphosphate (UDP) glucuronyl transferase (UDPGT) and the substrates uridine diphosphate glucuronic acid (UDPGA)
T J Hardt et al.
Arzneimittel-Forschung, 33(10), 1442-1446 (1983-01-01)
Blood concentration-time data of coumarin (C), 7-hydroxycoumarin (7-HC) and 7-hydroxycoumarin glucuronide (7-HCG) were obtained in rats receiving intraperitoneal doses of C ranging from 2.5 to 60 mg/kg and of 7-HC ranging from 2.5 to 20 mg/kg. Coumarin blood levels were
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| UC263-10MG | 04061832932088 |
| UC263-5MG | 04061832932095 |