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1607007

USP

Saccharin

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide

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Tamaño de envaseSKUDisponibilidadPrecio
200 mg
Comprobar disponibilidad del carrito
$445.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C7H5NO3S
Número CAS:
Peso molecular:
183.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6888

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grade

pharmaceutical primary standard

API family

saccharin

manufacturer/tradename

USP

mp

226-229 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Saccharin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Saccharin Sodium Tablets

Biochem/physiol Actions

A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Este artículo
S00400008.20128109185
Saccharin United States Pharmacopeia (USP) Reference Standard

USP

1607007

Saccharin

Saccharin European Pharmacopoeia (EP) Reference Standard

S0040000

Saccharin

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

-

format

neat

format

neat

format

-

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

mp

226-229 °C (lit.)

mp

226-229 °C (lit.)

mp

228-230 °C

mp

226-229 °C (lit.)

API family

saccharin

API family

saccharin

API family

-

API family

-


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11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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J Whysner et al.
Pharmacology & therapeutics, 71(1-2), 225-252 (1996-01-01)
Sodium saccharin (NaSac) produces bladder tumors consistently in male rats only after lifetime exposure that begins at birth. NaSac is not metabolized and is negative in most genotoxicity tests. NaSac-induced cell damage and proliferation have been proposed as important factors
The toxicological effects of saccharin in short-term genotoxicity assays.
D L Arnold et al.
Mutation research, 221(2), 69-132 (1989-09-01)
R L Anderson
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(7), 637-644 (1988-07-01)
An hypothesis is presented of a mechanism for the sodium saccharin (NaS)-associated tumorigenesis of the urinary bladder that occurs in male rats. The ingestion of high doses of NaS is associated with increased urine volume and bladder mass. In rats



Número de artículo de comercio global

SKUGTIN
1607007-200MG04061835345564

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