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S106

SR-95531

≥98% (HPLC), GABAA receptor antagonist , powder

Sinónimos:

2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide, Gabazine

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Tamaño de envaseSKUDisponibilidadPrecio
10 mg

Disponible para enviar HOYdesdeMILWAUKEE

$210.00
50 mg

Disponible para enviar HOYdesdeMILWAUKEE

$710.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C15H18BrN3O3
Número CAS:
Peso molecular:
368.23
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:

$210.00


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Nombre del producto

SR-95531, ≥98% (HPLC), powder

Quality Level

assay

≥98% (HPLC)

form

powder

color

white

solubility

H2O: >10 mg/mL

SMILES string

[Br-].COc1ccc(cc1)-c2ccc(N)[n+](CCCC(O)=O)n2

InChI

1S/C15H17N3O3.BrH/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20;/h4-9,16H,2-3,10H2,1H3,(H,19,20);1H

InChI key

GFZHNFOGCMEYTA-UHFFFAOYSA-N

Biochem/physiol Actions

SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Este artículo
SML0607SML0917PZ0285
form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: >10 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 25 mg/mL, clear

color

white

color

white to beige

color

white to beige

color

white to beige

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)
rat ... Gabra2(29706)

Gene Information

-

Gene Information

-

Gene Information

-


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Artículos

DISCOVER Bioactive Small Molecules for Neuroscience


Yicheng Xie et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(45), 14890-14900 (2014-11-08)
Relatively few studies have examined plasticity of inhibitory neuronal networks following stroke in vivo, primarily due to the inability to selectively monitor inhibition. We assessed the structure of parvalbumin (PV) interneurons during a 5 min period of global ischemia and
Le Chang et al.
Neuron, 77(3), 559-571 (2013-02-12)
Retinal specializations such as cone-photoreceptor opsin-expression gradients, as found in several vertebrate species, are intuitively considered detrimental to color vision. In mice, the majority of cones coexpress both "blue" and "green" opsin. The coexpression ratio changes along the dorsoventral axis
Marvin R Diaz et al.
PloS one, 8(1), e55673-e55673 (2013-02-06)
Cerebellar granule cells (CGNs) are one of many neurons that express phasic and tonic GABAergic conductances. Although it is well established that Golgi cells (GoCs) mediate phasic GABAergic currents in CGNs, their role in mediating tonic currents in CGNs (CGN-I(tonic))



Número de artículo de comercio global

SKUGTIN
S106-50MG04061836846367
S106-10MG04061836846350
SAB5200438-100UG04061832146386
SAB5200449-100UG04061832146492
SAB5200454-100UG04061832146546
SAB5200450-100UG04061832146508
SAB5200448-100UG04061832146485
SAB5200453-100UG04061832146539
SAB5200451-100UG04061832146515
SAB5200442-100UG04061832146423
SAB5200439-100UG04061832146393
SAB5200440-100UG04061832146409

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