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M6145

1-tioglicerol

liquid, BioReagent, suitable for cell culture, ≥97% (titration)

Sinónimos:

α-Monotioglicerol, α-Tioglicerol, 3-Mercapto-1,2-propanodiol

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Tamaño de envaseSKUDisponibilidadPrecio
25 mL

Disponible para enviar HOYdesdeMILWAUKEE

$108.00
100 mL

Disponible para enviar HOYdesdeMILWAUKEE

$257.00
250 mL

Disponible para enviar HOYdesdeMILWAUKEE

$579.00

Acerca de este artículo

Fórmula lineal:
HSCH2CH(OH)CH2OH
Número CAS:
Peso molecular:
108.16
UNSPSC Code:
12352211
NACRES:
NA.75
PubChem Substance ID:
EC Number:
202-495-0
Beilstein/REAXYS Number:
1732046
MDL number:

$108.00


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biological source

synthetic (organic)

Quality Segment

product line

BioReagent

assay

≥97% (titration)

form

liquid

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

refractive index

n20/D 1.527 (lit.)

bp

118 °C/5 mmHg (lit.)

solubility

water: miscible 0.1 M

density

1.25 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

InChI key

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

Application

En estudios de cultivo celular de neuronas corticales y de hipocampo embrionarias, líneas de mastocitos de médula ósea de ratón y líneas celulares humanas Β se ha utilizado el 1-tioglicerol como componente del medio de cultivo para estimular la proliferación.


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pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

210.2 °F - closed cup

flash_point_c

99 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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L Tang et al.
Journal of biomedical materials research, 41(2), 333-340 (1998-06-25)
Biomaterial-mediated complement activation repeatedly has been invoked as a trigger of phagocyte reactions and inflammation. However, a direct correlation between complement activation and inflammatory responses to biomaterial surfaces has yet to be established. Using an animal implantation model and gold
Morgan Oatley et al.
Nature communications, 11(1), 586-586 (2020-01-31)
The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). The intermediary steps of this process are unclear, in particular the identity of endothelial cells that give rise to HSPCs
Suji Lee et al.
Stem cells (Dayton, Ohio), 36(10), 1552-1566 (2018-07-14)
Although autologous induced pluripotent stem cells (iPSCs) can potentially be useful for treating patients without immune rejection, in reality it will be extremely expensive and labor-intensive to make iPSCs to realize personalized medicine. An alternative approach is to make use



Número de artículo de comercio global

SKUGTIN
M6145-100ML04061834060666
M6145-25ML04061834060680
M6145-250ML04061834060673

Questions

1–7 of 7 Questions  
  1. How long is degradation time of Monothioglycerol (MTG)? In other words, how long can I save it at room temperature ?

    1 answer
    1. The recommended storage temperature for this material is 2-8°C. However, the product ships at ambient temperature. Refrigerated products that ship at ambient temperature are considered stable up to 2 weeks for transit time. Additional stability studies have not been conducted.

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  2. After dilute with 0.1M with water How can we storage and how long can be stored?

    1 answer
    1. The solution stability of this product is not determined. Working solutions should be prepared fresh daily.

      Helpful?

  3. how long is this product stable if stored at room temperature?

    1 answer
    1. This product is assigned a retest date of 6 years from the date of quality release. In order to assure maximum qualtiy, the recommended storage temperature is 2 - 8 °C. However, several identical products available under other brands, such as 108703 or 88640, are stored at ambient temperature. The estimated shelf life of these items ranges from 1 - 2 years, when properly sealed and handled.

      Helpful?

  4. How long is degradation time of Monothioglycerol (MTG)? In other words, how long can I save it in the refrigerator?

    1 answer
    1. This product is not assigned an expiration date. It is assigned a recommended retest date of 5 years after the quality release date. It will be stable at 2 - 8 °C during this period if not contaminated and securely closed.

      A recommended retest date is the period during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.
      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

      Helpful?

  5. What is the concentration of the 1-thioglycerol?

    1 answer
    1. The liquid is not a solution of 1-thioglycerol in some solvent. Rather, it is a neat liquid (i.e., essentially pure 1-thioglycerol). Based on a density of 1.245 g/mL and a molecular weight of 108.2 g/mole, one can calculate an effective molarity of 11.5 M. This information may be found on the M1753 product information sheet.

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  6. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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