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M4699

MTEP hydrochloride

≥98% (HPLC), mGlu5 antagonist,

Sinónimos:

MTEP hydrochloride, 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine hydrochloride

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Tamaño de envaseSKUDisponibilidadPrecio
5 mg

Disponible para enviar HOYdesdeMILWAUKEE

$162.00
25 mg

Disponible para enviar HOYdesdeMILWAUKEE

$642.00
$545.70

Acerca de este artículo

Fórmula empírica (notación de Hill):
C11H8N2SHCl
Número CAS:
Peso molecular:
236.72
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Quality level:
Storage condition:
desiccated

$162.00


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Nombre del producto

MTEP hydrochloride, ≥98% (HPLC)

Quality Level

assay

≥98% (HPLC)

storage condition

desiccated

color

white to beige

solubility

H2O: 30 mg/mL, clear

originator

Merck & Co., Inc., Kenilworth, NJ, U.S.

storage temp.

2-8°C

SMILES string

Cl.Cc1nc(cs1)C#Cc2cccnc2

InChI

1S/C11H8N2S.ClH/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10;/h2-3,6-8H,1H3;1H

InChI key

YCIOJDKGCWAHLR-UHFFFAOYSA-N

Biochem/physiol Actions

MTEP is a potent and highly selective antagonist for mGluR5.
MTEP is a selective mGlu5 antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Este artículo
SML2784SML1610SML0588
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

H2O: 30 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: 15 mg/mL, clear

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

originator

Merck & Co., Inc., Kenilworth, NJ, U.S.

originator

-

originator

-

originator

-


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Artículos

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Rianne R Campbell et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(14), 2745-2761 (2019-02-10)
The bed nucleus of the stria terminalis (BNST) is part of the limbic-hypothalamic system important for behavioral responses to stress, and glutamate transmission within this region has been implicated in the neurobiology of alcoholism. Herein, we used a combination of
Tomas Ondrejcak et al.
Neurobiology of disease, 127, 582-590 (2019-03-27)
Soluble synaptotoxic aggregates of the main pathological proteins of Alzheimer's disease, amyloid β-protein (Aß) and tau, have rapid and potent inhibitory effects on long-term potentiation (LTP). Although the promotion of synaptic weakening mechanisms, including long-term depression (LTD), is posited to



Número de artículo de comercio global

SKUGTIN
M4699-25MG04061833219584
M4699-5MG04061833219591

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