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M104

(±)-Muscarine chloride hydrate

Name: (±)-Muscarine chloride hydrate
Brand: SIGMA
Price: 185 USD

≥98% (HPLC)

Sinónimos:

Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate

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Tamaño de envase	SKU	Disponibilidad	Precio
5 mg		Comprobar disponibilidad del carrito	$185.00
25 mg		Comprobar disponibilidad del carrito	$533.00

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Fórmula empírica (notación de Hill):

C₉H₂₀ClNO₂ · xH₂O

Número CAS:

2936-25-6

Peso molecular:

209.71 (anhydrous basis)

NACRES:

NA.77

PubChem Substance ID:

24278578

UNSPSC Code:

12352200

MDL number:

MFCD00055067

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

desiccated

$185.00

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Propiedades

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white

solubility

deionized water: ≥20 mg/mL

storage temp.

room temp

SMILES string

[Cl-].CC1OC(CC1O)C[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1

InChI key

WUFRNEJYZWHXLC-UHFFFAOYSA-M

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Descripción

Application

(±)-Muscarine chloride hydrate may be used:

as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments[1]
as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples[2]

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases.[3] Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.[3]

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Este artículo	M6532	A7410	SML0608
Sigma-Aldrich M104 (±)-Muscarine chloride hydrate	Sigma-Aldrich M6532 (+)-Muscarine chloride	Sigma-Aldrich A7410 Amiloride hydrochloride hydrate	Sigma-Aldrich SML0608 A-412997 dihydrochloride
assay ≥98% (HPLC)	assay ~95% (TLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100
storage temp. room temp	storage temp. -	storage temp. room temp	storage temp. room temp
storage condition desiccated	storage condition -	storage condition -	storage condition desiccated
solubility deionized water: ≥20 mg/mL	solubility H₂O: 50 mg/mL	solubility H₂O: 50 mg/mL, hazy (Very Faint Yellow to Dark Yellow and Very Faint Green-Yellow to Dark Green-Yellow and Very Faint Brown-Yellow to Dark Brown-Yellow)	solubility H₂O: 20 mg/mL, clear

pictograms

GHS07

signalword

Warning

hcodes

H302,H319

pcodes

P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Pharmacological actions of pure muscarine chloride.

P J FRASER

British journal of pharmacology and chemotherapy, 12(1), 47-52 (1957-03-01)

The action of chromatographically pure crystalline muscarine chloride, prepared from Amanita muscaria, has been compared with acetylcholine chloride (ACh) on a number of different organs from a variety of species. Muscarine caused spasm in vivo and in vitro of muscles

Chapter 67 - Mushroom Toxins

Puschner B

Veterinary Toxicology, 955-966 (2018)

Evaluation of novel organosilane modifications of paper spray mass spectrometry substrates for analyzing polar compounds.

Thomas P Bambauer et al.

Talanta, 204, 677-684 (2019-07-31)

Paper spray mass spectrometry (PSMS) is currently used in different analytical fields, but less effort has been made so far to use PSMS for highly polar compounds. Such analytes usually show poor performance in PSMS due to their high affinity

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SKU	GTIN
915998-1G	04065265677714
M104-25MG	04061832091792
M104-5MG	04061832091808

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(±)-Muscarine chloride hydrate

≥98% (HPLC)

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Acerca de este artículo

M104-5MG

$185.00

Quality Level

assay

form

storage condition

color

solubility

storage temp.

SMILES string

InChI

InChI key

Gene Information

Application

Biochem/physiol Actions

Features and Benefits

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Este artículo

Información de seguridad

pictograms

signalword

hcodes

pcodes

Hazard Classifications

Clase de almacenamiento

wgk

flash_point_f

flash_point_c

ppe

Documentación

Certificados de análisis (COA)

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