GS75
GST O1-1, Recombinant Human
Sinónimos:
GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R, glutathione S-transferase omega 1
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| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 100 μg | Comprobar disponibilidad del carrito | $442.00 |
Acerca de este artículo
NACRES:
NA.26
UNSPSC Code:
12352200
Form:
frozen liquid
Assay:
>95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
26 kDa
Servicio técnico
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Permítanos ayudarlebiological source
human
Quality Level
recombinant
expressed in E. coli
assay
>95% (SDS-PAGE)
form
frozen liquid
specific activity
4.21 units/mg protein
mol wt
26 kDa
concentration
1.98 mg/mL
storage temp.
−70°C
Gene Information
human ... GSTO1(9446)
General description
using spectrophotometric determination of 1-chloro-2,4-dinitrobenzene (CDNB) conjugation with reduced glutathione (1 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.
Biochem/physiol Actions
Glutathione S-transferase omega 1 (GSTO1) is an enzyme that in humans is encoded by the GSTO1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
Preparation Note
The enzyme should be used by the end-user customer within 1 year of receipt.
1 of 1
Este artículo | |||
|---|---|---|---|
| assay >95% (SDS-PAGE) | assay >95% (SDS-PAGE) | assay >95% (SDS-PAGE) | assay >95% (SDS-PAGE) |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli |
| biological source human | biological source human | biological source human | biological source human |
| concentration 1.98 mg/mL | concentration 3.17 mg/mL | concentration 1.52 mg/mL | concentration 1.01 mg/mL |
| form frozen liquid | form frozen liquid | form frozen liquid | form frozen liquid |
| mol wt 26 kDa | mol wt 26 kDa | mol wt 23 kDa | mol wt 25 kDa |
Clase de almacenamiento
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenido relacionado
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Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| GS75-100UG | 04061833656587 |