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F1678

R-(−)-Fluoxetine hydrochloride

Name: R-(−)-Fluoxetine hydrochloride
Brand: SIGMA
Price: 106.25 USD
Availability: InStock

>98% (HPLC), solid

Sinónimos:

(R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride

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Tamaño de envase	SKU	Disponibilidad	Precio
5 mg		Disponible para enviar HOYdesdeMILWAUKEE	$125.00 $106.25
25 mg		Disponible para enviar HOYdesdeMILWAUKEE	$441.00

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₁₇H₁₈NOF₃ · HCl

Número CAS:

114247-09-5

Peso molecular:

345.79

NACRES:

NA.77

PubChem Substance ID:

24278433

UNSPSC Code:

12352200

MDL number:

MFCD04040065

Assay:

>98% (HPLC)

Form:

solid

Storage condition:

desiccated

$106.25

Precio de catálogo$125.00Ahorre 15 %

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Propiedades

Quality Segment

100

assay

>98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H₂O: soluble >10 mg/mL

originator

Eli Lilly

SMILES string

Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1

InChI key

GIYXAJPCNFJEHY-PKLMIRHRSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Descripción

Application

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

to study its effects on the embryoid body (EB) morphogenesis[1]
in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips[2]
to study its effects as an endocrine disruption inducer in Pimephales promelas[3]

Biochem/physiol Actions

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.[3]

Selective serotonin reuptake inhibitor.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Este artículo	F132	343290	M2824
Sigma-Aldrich F1678 R-(−)-Fluoxetine hydrochloride	Sigma-Aldrich F132 Fluoxetine hydrochloride	Sigma-Aldrich 343290 Fluoxetine, Hydrochloride	Sigma-Aldrich M2824 Meptazinol hydrochloride
form solid	form solid	form solid	form powder
assay >98% (HPLC)	assay -	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
storage condition desiccated	storage condition -	storage condition OK to freeze, desiccated (hygroscopic), protect from light	storage condition -
solubility H₂O: soluble >10 mg/mL	solubility H₂O: 4 mg/mL, DMSO: >5 mg/mL	solubility methanol: 100 mg/mL, water: 5 mg/mL	solubility H₂O: >10 mg/mL
color white	color white	color -	color white to off-white