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E1127

β-Estradiol 17-(β-D-glucuronide) sodium salt

Name: &#946;-Estradiol 17-(&#946;-<SC>D</SC>-glucuronide) sodium salt
Brand: SIGMA
Price: 111 USD
Availability: InStock

≥98% (HPLC), Estradiol metabolite, powder

Sinónimos:

1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide

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Tamaño de envase	Disponibilidad	Precio
5 mg	Disponible para enviar HOYdesdeMILWAUKEE	$111.00
10 mg	Disponible para enviar HOYdesdeMILWAUKEE	$217.00
25 mg	Disponible para enviar HOYdesdeMILWAUKEE	$367.00
100 mg	Disponible para enviar HOYdesdeMILWAUKEE	$1,060.00

Acerca de este artículo

Fórmula lineal:

C₂₄H₃₁O₈Na

Número CAS:

15087-02-2

Peso molecular:

470.49

UNSPSC Code:

51111800

PubChem Substance ID:

24894388

NACRES:

NA.77

MDL number:

MFCD00056557

Assay:

≥98% (HPLC)

Form:

powder

$111.00

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Propiedades

Nombre del producto

β-Estradiol 17-(β-D-glucuronide) sodium salt,

sterility

non-sterile

Quality Segment

200

assay

≥98% (HPLC)

form

powder

solubility

0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O

InChI

1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;

InChI key

GPLPNZUTAJWRLU-UHFFFAOYSA-N

Descripción

Application

β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay. It has also been used as a constituent of modified synthetic oviduct fluid (m-SOF) for maturation of bovine cumulus oocyte complexes (COC).

Biochem/physiol Actions

Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Este artículo	E2127	E2128	E9505
Sigma-Aldrich E1127 β-Estradiol 17-(β-D-glucuronide) sodium salt	Sigma-Aldrich E2127 β-Estradiol 3-(β-D-glucuronide) sodium salt	Sigma-Aldrich E2128 β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt	Sigma-Aldrich E9505 β-Estradiol 3-sulfate sodium salt
form powder	form powder	form powder	form powder
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥93%
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. room temp
solubility 0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow	solubility water: 10 mg/mL, clear to slightly hazy	solubility water: 50 mg/mL, clear, colorless	solubility methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
shipped in ambient	shipped in ambient	shipped in ambient	shipped in ambient