D4292

3,3′-Dioctadecyloxacarbocyanine perchlorate

Name: 3,3&#8242;-Dioctadecyloxacarbocyanine perchlorate
Brand: SIGMA
Price: 124 USD
Availability: InStock

≥98% purity (TLC), powder

Sinónimos:

DiOC₁₈(3), DiO

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20 MG

$124.00

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Fórmula empírica (notación de Hill):

C₅₃H₈₅ClN₂O₆

Número CAS:

34215-57-1

Peso molecular:

881.70

NACRES:

NA.47

PubChem Substance ID:

24893855

UNSPSC Code:

12171500

MDL number:

MFCD00132951

Beilstein/REAXYS Number:

4122771

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Nombre del producto

3,3′-Dioctadecyloxacarbocyanine perchlorate,

assay

≥98% (TLC)

form

powder

technique(s)

titration: suitable

color

orange

solubility

chloroform: 50 mg/mL

fluorescence

λ_ex 484 nm; λ_em 501 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[O-]Cl(=O)(=O)=O.CCCCCCCCCCCCCCCCCCN1C(\Oc2ccccc12)=C/C=C/c3oc4ccccc4[n+]3CCCCCCCCCCCCCCCCCC

InChI

1S/C53H85N2O2.ClHO4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-37-46-54-48-40-33-35-42-50(48)56-52(54)44-39-45-53-55(49-41-34-36-43-51(49)57-53)47-38-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;2-1(3,4)5/h33-36,39-45H,3-32,37-38,46-47H2,1-2H3;(H,2,3,4,5)/q+1;/p-1

InChI key

GFZPJHFJZGRWMQ-UHFFFAOYSA-M

Categorías relacionadas

Clinical & Diagnostics

Hematology Stains

Histology Stains

Tissue Diagnostics

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Este artículo	318426	E9379	318434
D4292 3,3′-Dioctadecyloxacarbocyanine perchlorate	318426 3,3′-Dihexyloxacarbocyanine iodide	Sigma-Aldrich E9379 Stains-All	Sigma-Aldrich 318434 3,3′-Dipropylthiacarbocyanine iodide
technique(s) titration: suitable	technique(s) titration: suitable	technique(s) microbe id \| staining: suitable	technique(s) -
fluorescence λ_ex 484 nm; λ_em 501 nm in methanol	fluorescence λ_ex 485 nm; λ_em 501 nm in methanol	fluorescence -	fluorescence λ_ex 559 nm; λ_em 575 nm in methanol
color orange	color -	color -	color -
form powder	form powder or chunks	form powder	form crystalline powder
application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology
solubility chloroform: 50 mg/mL	solubility chloroform: 25 mg/mL, clear to slightly hazy, orange	solubility chloroform: 40 mg (PLUS 4.0 ml)	solubility chloroform/methanol: 10 mg/mL, clear

Application

3,3′-Dioctadecyloxacarbocyanine perchlorate has been used for lipid bilayer labeling in antigen-presenting cells. It has also been used as a lipophilic dye for labeling in zebrafish embryos.[1]

Biochem/physiol Actions

3,3′-Dioctadecyloxacarbocyanine perchlorate is a fluorescent probe of lipid bilayer model membranes.[2] It is a fluorescent marker for living cells in culture.[3]

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads.

Jayesh A Kulkarni et al.

Nanoscale, 11(18), 9023-9031 (2019-04-26)

The success of Onpattro™ (patisiran) clearly demonstrates the utility of lipid nanoparticle (LNP) systems for enabling gene therapies. These systems are composed of ionizable cationic lipids, phospholipid, cholesterol, and polyethylene glycol (PEG)-lipids, and are produced through rapid-mixing of an ethanolic-lipid

A simple trogocytosis-based method to detect, quantify, characterize and purify antigen-specific live lymphocytes by flow cytometry, via their capture of membrane fragments from antigen-presenting cells.

Daubeuf S, et al.

Nature Protocols, 1, 2536-2536 (2006)

Layer-by-Layer 3D Constructs of Fibroblasts in Hydrogel for Examining Transdermal Penetration Capability of Nanoparticles.

Xiaochun Hou et al.

SLAS technology, 22(4), 447-453 (2016-06-22)

Nanoparticles are emerging transdermal delivery systems. Their size and surface properties determine their efficacy and efficiency to penetrate through the skin layers. This work utilizes three-dimensional (3D) bioprinting technology to generate a simplified artificial skin model to rapidly screen nanoparticles

Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization.

Maria B C de Matos et al.

Frontiers in pharmacology, 10, 1463-1463 (2019-12-24)

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose to encapsulate ML1 in a nanocarrier

Strategy for constructing vascularized adipose units in poly(l-glutamic acid) hydrogel porous scaffold through inducing in-situ formation of ASCs spheroids.

Kunxi Zhang et al.

Acta biomaterialia, 51, 246-257 (2017-01-18)

Vascularization is of great importance to adipose tissue regeneration. Here we introduced a paradigm that using scaffold to induce ASC spheroids, so to promote vascularized adipose tissue regeneration. Poly (l-glutamic acid) (PLGA) was activated by EDC, followed by being cross-linked

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SKU	GTIN
D4292-20MG	04061833564264

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