Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

C8221

Sigma-Aldrich

Caffeic acid phenethyl ester

Caffeic acid phenethyl ester

≥97% (HPLC), powder

Sinónimos:

CAPE

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Seleccione un Tamaño

1 G
$589.50

$589.50

Precio de catálogo$655.00Ahorre 10 %
Web-Only Promotion

Disponible para envío el07 de abril de 2025Detalles

Solicitar un pedido a granel
Todas las fotos(1)

Seleccione un Tamaño

Cambiar Vistas
1 G
$589.50

About This Item

Fórmula empírica (notación de Hill):
C17H16O4
Número de CAS:
104594-70-9
Peso molecular:
284.31
Número MDL:
MFCD00866470
Código UNSPSC:
12352108
ID de la sustancia en PubChem:
24278341
NACRES:
NA.77

$589.50

Precio de catálogo$655.00Ahorre 10 %
Web-Only Promotion

Disponible para envío el07 de abril de 2025Detalles

Solicitar un pedido a granel

origen biológico

synthetic

Ensayo

≥97% (HPLC)

Formulario

powder

condiciones de almacenamiento

protect from light

color

off-white

solubilidad

ethyl acetate: 50 mg/mL
DMSO: soluble
ethanol: soluble

temp. de almacenamiento

−20°C

cadena SMILES

Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O

InChI

1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+

Clave InChI

SWUARLUWKZWEBQ-VQHVLOKHSA-N

Información sobre el gen

human ... NFKB2(4791)

Aplicación

Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism,[1] as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231,[2] to study its effects on amiodarone-induced pulmonary fibrosis in rats.[3]

Acciones bioquímicas o fisiológicas

CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion.[1] It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.[2]
Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.

Características y beneficios

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
BCCM2256
BCCK6390
BCCC6847
BCBV6787
BCBR2913V

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 3

1 of 3

Ethyl 4-hydroxy-3-methoxycinnamate 98%

Sigma-Aldrich

320617

Ethyl 4-hydroxy-3-methoxycinnamate

Caffeic acid matrix substance for MALDI-MS, ≥99.0% (HPLC)

Supelco

60018

Caffeic acid

3,4-Dihydroxyhydrocinnamic acid 98%

Sigma-Aldrich

102601

3,4-Dihydroxyhydrocinnamic acid

Attenuation of oxidative stress in plasma and tissues of rats with experimentally induced hyperthyroidism by caffeic acid phenylethyl ester
Mohamadin AM, et al.
Basic and Clinical Pharmacology and Toxicology, 100(2), 84-90 (2007)
K Natarajan et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(17), 9090-9095 (1996-08-20)
Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives, is known to have antimitogenic, anticarcinogenic, antiinflammatory, and immunomodulatory properties. The molecular basis for these diverse properties is not known. Since the role of the nuclear factor
M T Hansen et al.
Oncogene, 34(4), 424-435 (2014-01-29)
S100A4 is implicated in metastasis and chronic inflammation, but its function remains uncertain. Here we establish an S100A4-dependent link between inflammation and metastatic tumor progression. We found that the acute-phase response proteins serum amyloid A (SAA) 1 and SAA3 are
Z Z Su et al.
Cancer research, 54(7), 1865-1870 (1994-04-01)
The active component of the honeybee hive product propolis, caffeic acid phenethyl ester (CAPE), induces a selective growth suppressive and toxic effect toward cloned rat embryo fibroblast cells transformed by adenovirus type 5 (Ad5) or the Ad5 E1A transforming gene
Migration rate inhibition of breast cancer cells treated by caffeic acid and caffeic acid phenethyl ester: an in vitro comparison study
Kabala-Dzik A, et al.
Nutrients, 9(10), 1144-1144 (2017)
Ver todos los artículos relacionados

Artículos

NF-κB and Inflammation

Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

1 Review This action will navigate to reviews.

Questions

Reviews

Active Filters

  1. 1 Ratings-Only Review

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico