C1355

Z-Leu-Glu(O-Me)-His-Asp(O-Me) fluoromethyl ketone trifluoroacetate salt hydrate

≥90%

• Sinónimos: Z-LEHD-FMK, Z-LE(OMe)HD(OMe)-FMK
• Fórmula empírica (notación de Hill): C₃₂H₄₃FN₆O₁₀ · xC₂HF₃O₂ · yH₂O
• Número CAS: 210345-04-3
• Peso molecular: 690.72 (anhydrous free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774878
• MDL number: MFCD01862609

Propiedades

• assay: ≥90%
• form: film
• storage condition: desiccated
• color: colorless to light brown
• solubility: DMSO: 10 mg/mL, clear
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)/t22-,23-,24-,25-/m0/s1
• InChI key: YXRKBEPGVHOXSV-QORCZRPOSA-N

Descripción

Application

A cell-permeable inhibitor of caspase-9, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)