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A9043

S-Acetylthioglycolic acid N-hydroxysuccinimide ester

≥95% (TLC), powder

Sinónimos:

N-Succinimidyl (acetylthio)acetate, N-Succinimidyl S-acetylthioglycolate, S-Acetylthioglycolic acid NHS ester, SATA

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Tamaño de envaseSKUDisponibilidadPrecio
10 mg

Envío estimado HOYdesdeSAINT LOUIS

$53.70
50 mg

Envío estimado HOYdesdeSAINT LOUIS

$101.00
100 mg

Envío estimado HOYdesdeSAINT LOUIS

$165.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C8H9NO5S
Número CAS:
Peso molecular:
231.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7815491
Assay:
≥95% (TLC)
Form:
powder

$53.70


Envío estimado HOYDetalles


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Quality Level

assay

≥95% (TLC)

form

powder

solubility

acetonitrile: 50 mg/mL, DMF: soluble

storage temp.

−20°C

SMILES string

CC(=O)SCC(=O)ON1C(=O)CCC1=O

InChI

1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3

InChI key

FLCQLSRLQIPNLM-UHFFFAOYSA-N

Application

Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Other Notes

Note that the ester couples very efficiently to primary amines compared to other thiolating reagents. In addition, this reagent will neutralize original amine positive charge.

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Este artículo
55156M9794B3295
assay

≥95% (TLC)

assay

≥95.0% (coupling assay to aminopropyl silica gel)

assay

≥98%

assay

≥95% (TLC)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

solubility

acetonitrile: 50 mg/mL, DMF: soluble

solubility

DMF: soluble, DMSO: soluble

solubility

chloroform: 100 mg/mL, DMF: soluble (lit.)(lit.)

solubility

DMF: 25 mg/mL

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

-

form

powder

form

powder


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Magnus Bergkvist et al.
Methods in molecular biology (Clifton, N.J.), 751, 381-400 (2011-06-16)
Over the last decade, scanning probe microscopy (SPM) techniques, such as atomic force microscopy (AFM), have played an important role in a variety of biophysical research efforts. This straightforward technique has the capability to measure forces down to a few
Screening of monoclonal antibodies using antigens labeled with acetylcholinesterase.
Y Frobert et al.
Methods in molecular biology (Clifton, N.J.), 80, 57-68 (1998-07-17)
A Delmas et al.
Bioconjugate chemistry, 3(1), 80-84 (1992-01-01)
We have previously shown that the carrier polytuftsin obtained by polycondensation of tuftsin, a naturally occurring macrophage activator, increases significantly the antibody response against a linked B-epitope. In the present work, we have studied the influence of different cross-linking reagents



Número de artículo de comercio global

SKUGTIN
A9043-50MG04061832421339
A9043-10MG04061832421322
A9043-100MG04061832421315

Questions

  1. Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,

    1 answer
    1. The product impurities are not identified or quantified. Please see the product specification sheet:
      https://www.sigmaaldrich.com/specification-sheets/457/256/A9043-BULK________SIGMA____.pdf.

      Helpful?

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