A5730

Abz-SDK(Dnp)P-OH trifluoroacetate salt

≥91% (HPLC), lyophilized powder

• Sinónimos: o-aminobenzoic acid-Ser-Asp-Lys(DNP)Pro-OH trifluoroacetate salt
• Fórmula empírica (notación de Hill): C₃₁H₃₈N₈O₁₃ · xC₂HF₃O₂
• Número CAS: 1217465-57-0
• Peso molecular: 730.68 (free base basis)
• NACRES: NA.77
• PubChem Substance ID: 24891013
• UNSPSC Code: 12352200
• MDL number: MFCD09753055
• Assay: ≥91% (HPLC)
• Form: lyophilized powder

Propiedades

• Quality Segment: 100
• assay: ≥91% (HPLC)
• form: lyophilized powder
• solubility: H₂O: freely soluble
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(F)(F)F.Nc1ccccc1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)C(=O)N3CCC[C@H]3C(O)=O
• InChI: 1S/C31H38N8O13.C2HF3O2/c32-19-7-2-1-6-18(19)27(43)36-23(16-40)29(45)35-22(15-26(41)42)28(44)34-21(30(46)37-13-5-9-24(37)31(47)48)8-3-4-12-33-20-11-10-17(38(49)50)14-25(20)39(51)52;3-2(4,5)1(6)7/h1-2,6-7,10-11,14,21-24,33,40H,3-5,8-9,12-13,15-16,32H2,(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H,47,48);(H,6,7)/t21-,22-,23-,24-;/m0./s1
• InChI key: IFSUGURCQHMSJS-JPIABUGISA-N

Descripción

Application

Abz-SDK(Dnp)P-OH trifluoroacetate is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that specifically binds to the N domain of ACE. Abz-SDK(Dnp)P-OH has been used to study tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells.

Biochem/physiol Actions

Abz-SDK(Dnp)P-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the N domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable