73156

N-Methyl-L-serine

≥98% (TLC)

• Sinónimos: (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• Fórmula empírica (notación de Hill): C₄H₉NO₃
• Número de CAS: 2480-26-4
• Peso molecular: 119.12
• Beilstein/REAXYS Number: 2498641
• MDL number: MFCD00037756
• UNSPSC Code: 12352202
• PubChem Substance ID: 329764666
• NACRES: NA.32

Propiedades

• assay: ≥98% (TLC)
• form: powder
• optical activity: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• composition: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• color: white
• mp: 204 °C
• SMILES string: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• InChI key: PSFABYLDRXJYID-VKHMYHEASA-N

Descripción

Biochem/physiol Actions

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts.

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable