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51797

Atto MB2 maleimide

Methylene Blue derivative, ≥90% (HPLC)

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Tamaño de envaseSKUDisponibilidadPrecio
1 mg
Comprobar disponibilidad del carrito
$240.00

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NACRES:
NA.32
UNSPSC Code:
12352111

$240.00


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Quality Level

assay

≥90% (HPLC), ≥90% (degree of coupling)

form

solid

manufacturer/tradename

ATTO-TEC GmbH

λ

in ethanol (with 0.1% trifluoroacetic acid)

UV absorption

λ: 655-661 nm Amax

storage temp.

−20°C

Application

ATTO MB2 is a derivative of the well-known redox dye Methylene Blue. The dye can be reversibly reduced to the colorless leuko form. Upon oxidation the dye recovers and the absorption is fully restored. In common with most ATTO-labels the dye shows a high extinction coefficient. The dye is moderately hydrophilic. ATTO MB2 is a cationic dye. After coupling to a substrate the dye carries a net electrical charge of +1. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides react more selectively with thiols. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

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Este artículo
806617599953404
form

solid

form

powder

form

powder

form

-

assay

≥90% (HPLC), ≥90% (degree of coupling)

assay

≥90% (coupling rate)

assay

≥90% (HPLC), ≥90% (coupling of degree)

assay

≥90% (HPLC), ≥90% (degree of coupling)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

ATTO-TEC GmbH

manufacturer/tradename

ATTO-TEC GmbH

manufacturer/tradename

ATTO-TEC GmbH

manufacturer/tradename

ATTO-TEC GmbH

UV absorption

λ: 655-661 nm Amax

UV absorption

-

UV absorption

λ: 667-673 nm Amax

UV absorption

λ: 454-460 nm Amax


Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Chronic wounds are typically halted in the inflammatory stage of wound healing secondary to a prolonged inflammatory response of the body to bacterial colonization, as planktonic bacteria and biofilm and senescent cells present at the wound's edges. Surgical debridement of
Methylene blue as the safest blue dye for sentinel node mapping: emphasis on anaphylaxis reaction.
Sadeghi Ramin et al.
Acta oncologica (Stockholm, Sweden), 50(5), 729-731 (2011-03-19)
Aleksandra K Bruchey et al.
American journal of pharmacology and toxicology, 3(1), 72-79 (2008-01-01)
The goals of this review were to identify methylene blue (MB) as a compound that follows hormetic behavior for a wide range of effects and to address the question of what is unique about MB that could account for its



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SKUGTIN
51797-1MG04061823368049

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