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10419

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate

Name: 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate
Brand: SIGMA
Price: 309 USD
Availability: InStock

suitable for fluorescence, ≥95.0% (T)

Sinónimos:

1,8-ANS magnesium salt, ANSA magnesium salt, Magnesium 8-anilino-1-naphthalenesulfonate hydrate, N-Phenyl peri acid magnesium salt

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Tamaño de envase	SKU	Disponibilidad	Precio
25 g		Disponible para enviar HOYdesdeMILWAUKEE	$309.00

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Fórmula empírica (notación de Hill):

C₁₆H₁₂Mg_0.5NO₃S · xH₂O

Número CAS:

18108-68-4

Peso molecular:

310.49 (anhydrous basis)

UNSPSC Code:

12171500

NACRES:

NA.47

PubChem Substance ID:

329749053

EC Number:

242-004-7

Beilstein/REAXYS Number:

4834623

MDL number:

MFCD16661224

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Propiedades

Quality Level

200

assay

≥95.0% (T)

form

powder

technique(s)

titration: suitable

solubility

hot water: 50 mg/mL, green

λ_max

465-475 nm

fluorescence

λ_ex 388 nm; λ_em 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA

suitability

suitable for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O.[Mg++].[O-]S(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12.[O-]S(=O)(=O)c4cccc5cccc(Nc6ccccc6)c45

InChI

1S/2C16H13NO3S.Mg.H2O/c2*18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;;/h2*1-11,17H,(H,18,19,20);;1H2/q;;+2;/p-2

InChI key

FBANPIUXAXTAFX-UHFFFAOYSA-L

Descripción

General description

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

Features and Benefits

Fluorescent probe for the estimation of the CMC of surfactants.[1]

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Este artículo	A1028	A5144	10417
Sigma-Aldrich 10419 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate	Sigma-Aldrich A1028 8-Anilino-1-naphthalenesulfonic acid	Sigma-Aldrich A5144 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate	Sigma-Aldrich 10417 8-Anilino-1-naphthalenesulfonic acid ammonium salt
suitability suitable for fluorescence	suitability -	suitability suitable for fluorescence	suitability suitable for fluorescence
technique(s) titration: suitable	technique(s) -	technique(s) -	technique(s) -
fluorescence λ_ex 388 nm; λ_em 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA	fluorescence -	fluorescence -	fluorescence λ_ex 388 nm; λ_em 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA
form powder	form powder	form powder	form solid
solubility hot water: 50 mg/mL, green	solubility DMF: 50 mg/mL	solubility H₂O: 50 mg/mL	solubility H₂O: 0.1 g/5mL, clear to very slightly hazy (hot), NaOH: 1 N, H₂O: soluble, acetone: soluble, methanol: soluble
application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) -

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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The identification of hydrophobic sites on the surface of proteins using absorption difference spectroscopy of bromophenol blue.

M Bertsch et al.

Analytical biochemistry, 313(2), 187-195 (2003-02-28)

Hydrophobic sites on the surface of protein molecules are thought to have important functional roles. The identification of such sites can provide information about the function and mode of interaction with other cellular components. While the fluorescence enhancement of polarity-sensitive

Metal-catalyzed oxidation of brain-derived neurotrophic factor (BDNF): selectivity and conformational consequences of histidine modification.

J L Jensen et al.

Cellular and molecular biology (Noisy-le-Grand, France), 46(3), 685-696 (2000-06-29)

We have studied the metal-catalyzed oxidation (MCO) of brain-derived neurotrophic factor (BDNF) with regard to target sites and potential conformational changes of the protein. The exposure of BDNF to three different levels of ascorbate/Cu(II)/O2 [20 microM Cu(II), 2 mM ascorbate

Detection of an unfolding intermediate in alpha-urease with enhanced affinity for ANSA.

C D Peters et al.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(1), 55-61 (1997-01-01)

Protein aggregation is believed to be due to conformers that expose hydrophobic clusters that promote protein association. Such conformers can be detected using a fluorescent probe like 8-anilino 1-naphthalenesulfonic acid (ANSA). Here we show that urease exposed to 1.0 M

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SKU	GTIN
10419-25G	04061833415078
10419-1G	04061838671370

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