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MilliporeSigma

01409

Sigma-Aldrich

Lithium potassium acetyl phosphate

purum p.a., substrate (for phosphotransacetylase), ≥97.0% (NT)

Sinónimos:

Acetyl phosphate lithium potassium salt

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About This Item

Fórmula lineal:
CH3COOP(O)(OK)(OLi)
Número de CAS:
Peso molecular:
184.06
Beilstein/REAXYS Number:
5689718
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

grade

substrate (for phosphotransacetylase)
purum p.a.

assay

≥97.0% (NT)

form

powder

mp

>300 °C (lit.)

solubility

water: 25 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Li+].[K+].CC(=O)OP([O-])([O-])=O

InChI

1S/C2H5O5P.K.Li/c1-2(3)7-8(4,5)6;;/h1H3,(H2,4,5,6);;/q;2*+1/p-2

InChI key

RLQMPLKXFIXRCV-UHFFFAOYSA-L

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General description

Lithium potassium acetyl phosphate is an organometallic compound that is used as a phosphoryl group donor. It is commonly used in protein phosphorylation reactions.

Application

Lithium potassium acetyl phosphate has been used as a component of cocktail A in evaluating the activity of choline acetyltransferase in mice brain tissue homogenates.

Biochem/physiol Actions

Lithium potassium acetyl phosphate is suitable as a source of acetyl phosphate. It is suitable for reducing inorganic monophosphate by-product formation by replacing inorganic oligophosphates in phosphatase-catalyzed transphosphorylation.

Other Notes

Energy-rich compound for the regeneration of adenosine-5′-triphosphate, ATP, and other triphosphates

pictograms

Health hazardCorrosion

signalword

Danger

hcodes

Hazard Classifications

Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Enzymatic regeneration of adenosine 5'-triphosphate: acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-alpha-D-ribosyl pyrophosphate, uridine-5'-diphosphoglucose.
D C Crans et al.
Methods in enzymology, 136, 263-280 (1987-01-01)
Sumonto Mitra et al.
Frontiers in aging neuroscience, 13, 714186-714186 (2021-09-04)
Gradual decline in cholinergic transmission and cognitive function occurs during normal aging, whereas pathological loss of cholinergic function is a hallmark of different types of dementia, including Alzheimer's disease (AD), Lewy body dementia (LBD), and Parkinson's disease dementia (PDD). Glial
Emiko Kinoshita-Kikuta et al.
PloS one, 10(7), e0132598-e0132598 (2015-07-08)
Hybrid sensor kinase, which contains a histidine kinase (HK) domain, a receiver domain, and a histidine-containing phosphotransmitter (HPt) domain, conveys signals to its cognate response regulator by means of a His-Asp-His-Asp phosphorelay. We examined the multistep phosphorelay of a recombinant

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