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438192

Anti-LRP, Light Chain Mouse mAb (5A6)

liquid, clone 5A6, Calbiochem®

Sinónimos:

Anti-Low Density Lipoprotein Receptor-Related Protein

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Tamaño de envaseSKUDisponibilidadPrecio
100 μg
Comprobar disponibilidad del carrito
$490.00

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NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
5A6, monoclonal
Species reactivity:
rabbit, mouse, human
Application:
Citations:
7

$490.00


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biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

5A6, monoclonal

form

liquid

does not contain

preservative

species reactivity

rabbit, mouse, human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Frozen Sections (1-5 µg/mL)
Immunoblotting (1-5 µg/mL)
Paraffin Sections (1-5 µg/mL, )

isotype

IgG2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LRP1(4035)

General description

Purified mouse monoclonal antibody. Recognizes the ~85 kDa LRP light chain protein under non-reducing conditions.
Recognizes the ~85 kDa LRP protein.
This Anti-LRP, Light Chain Mouse mAb (5A6) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of LRP, Light Chain.

Immunogen

Human
purified, human placenta LRP

Application

Frozen Sections (1-5 µg/ml)

Immunoblotting (1-5 µg/ml)

Paraffin Sections (1-5 µg/ml, see application references)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Mikhailenko, I., et al. 2001. J. Biol. Chem.276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res.87, 238.
Coukos, G., et al. 1994. Am. J. Pathol.144, 383.
Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb.14, 2017.
Strickland, D.K., et al. 1990. J. Biol. Chem.265, 17401.
Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Este artículo
438190MABN1796SAB1300316
antibody form

purified antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

Gene Information

human ... LRP1(4035)

Gene Information

human ... LRP1(4035)

Gene Information

human ... LRP1(4035)

Gene Information

human ... LRP3(4037)

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

species reactivity

rabbit, mouse, human

species reactivity

human

species reactivity

human, mouse

species reactivity

human

clone

5A6, monoclonal

clone

8G1, monoclonal

clone

6F8, monoclonal

clone

polyclonal

form

liquid

form

liquid

form

-

form

buffered aqueous solution


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Junling Yang et al.
Journal of molecular neuroscience : MN, 49(2), 277-288 (2012-09-05)
We previously reported that anti-amyloid-beta (Aβ) single-chain antibody (scFv59) brain delivery via recombinant adeno-associated virus (rAAV) was effective in reducing cerebral Aβ load in an Alzheimer's disease (AD) mouse model without inducing inflammation. Here, we investigated the prophylactic effects and
Abhay P Sagare et al.
The Journal of biological chemistry, 288(21), 15154-15166 (2013-04-13)
Soluble low density lipoprotein receptor-related protein-1 (sLRP1) binds ~70% of amyloid β-peptide (Aβ) in human plasma. In Alzheimer disease (AD) and individuals with mild cognitive impairment converting to AD, plasma sLRP1 levels are reduced and sLRP1 is oxidized, which results
Robert D Bell et al.
Nature cell biology, 11(2), 143-153 (2008-12-23)
Amyloid beta-peptide (Abeta) deposition in cerebral vessels contributes to cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD). Here, we report that in AD patients and two mouse models of AD, overexpression of serum response factor (SRF) and myocardin (MYOCD) in



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SKUGTIN
438192-100UG07790788050283

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