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407293

α-Interferon, Mouse, Recombinant, E. coli

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Tamaño de envaseSKUDisponibilidadPrecio
100 kU
Comprobar disponibilidad del carrito
$887.00

Acerca de este artículo

NACRES:
NA.32
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)

$887.00


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description

Merck USA index - 14, 4990

Quality Level

assay

≥95% (SDS-PAGE)

form

liquid

specific activity

≥3.5 x 104 units/mL

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Recombinant, mouse α-interferon expressed in E. coli. Antiviral, antineoplastic agent. Expressed during the triggering stage of macrophage cytocidal activation. Suppresses bone marrow function and cell proliferation. Modulates the immune response. Also known to induce apoptotic cell death in non-melanoma skin cancer.

Other Notes

Krishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer61, 110.
Dianzani, F. 1993. Gut34, 574.
Brouty-Boyce, D., and Zetter, B.R. 1990. Science208, 516.
Sidky, Y.A., and Borden, E.C. 1987. Cancer Res.47, 5155.
Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol.119, 34.
Pestka, S. 1986. Methods Enzymol.119, 14.
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Johnson, M.D., et al. 1981. Methods Enzymol.78, 394.
Rubinstein, S., et al. 1981. J. Virol.37, 755.
One unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Este artículo
407320407617575001
assay

≥95% (SDS-PAGE)

assay

≥95% (RP-HPLC, FPLC, and SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

form

liquid

form

lyophilized

form

lyophilized

form

liquid

shipped in

wet ice

shipped in

wet ice

shipped in

ambient

shipped in

wet ice

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C

storage temp.

−20°C

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, desiccated

storage condition

OK to freeze

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

specific activity

≥3.5 x 104 units/mL

specific activity

-

specific activity

-

specific activity

-


Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

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W Markland et al.
Antimicrobial agents and chemotherapy, 44(4), 859-866 (2000-03-18)
The enzyme IMP dehydrogenase (IMPDH) catalyzes an essential step in the de novo biosynthesis of guanine nucleotides, namely, the conversion of IMP to XMP. The major event occurring in cells exposed to competitive IMPDH inhibitors such as ribavirin or uncompetitive



Número de artículo de comercio global

SKUGTIN
407293-100KU04055977188196

Questions

  1. In what buffer is the interferon? what is the pH? if one needs to dilute, what is your recommendation?

    1 answer
    1. The buffer is phosphate-buffered saline (PBS) at a pH of approximately 7 ± 0.2, containing 0.1% bovine serum albumin (BSA). For dilution, it is recommended to use buffers that contain protein, such as 0.1% BSA.

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