Saltar al contenido
MilliporeSigma

Saltar a

05-666

Anti-BRCA2 Antibody, clone 5.23

clone 5.23, Upstate®, from mouse

Sinónimos:

Anti BRCC2, Anti-BROVCA2, Anti-FACD, Anti-FAD, Anti-FAD1, Anti-FANCD, Anti-FANCD1, Anti-GLM3, Anti-PNCA2, Anti-XRCC11

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas
Tamaño de envaseSKUDisponibilidadPrecio
200 μg
Comprobar disponibilidad del carrito
$490.00

Acerca de este artículo

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
5.23, monoclonal
Application:
ICC, WB
Citations:
15

$490.00


Comprobar disponibilidad del carrito
Está disponible un anticuerpo recombinante y sin conservantes para su diana. Pruebe ZRB2563

Solicite una orden a granel
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle


biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

5.23, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BRCA2(675)

General description

390kDa

Immunogen

GST fusion protein to residues 2959-3418 of human BRCA2 protein

Application

Detect BRCA2 with Anti-BRCA2 Antibody, clone 5.23 (Mouse Monoclonal Antibody), that has been shown to work in WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

BRCA2

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide.
Format: Purified
Protein G Chromatography

Preparation Note

Store at 2-8°C. Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at 2-8°C.

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
routinely evaluated by immunoblot on in HeLa nuclear extract

Other Notes

Due to license agreement restrictions, this product cannot be purchased for resale.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 1

Este artículo
16-23307-434HPA026815
antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

serum

antibody form

affinity isolated antibody

clone

5.23, monoclonal

clone

4.47, monoclonal

clone

polyclonal

clone

polyclonal

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

rabbit

species reactivity

human

species reactivity

human, rat, mouse

species reactivity

human

species reactivity

human

conjugate

unconjugated

conjugate

ALEXA FLUOR 488

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... BRCA2(675)

Gene Information

human ... PTK2(5747)

Gene Information

human ... BRCA1(672)

Gene Information

human ... BRCA2(675)


Still not finding the right product?

Pruebe nuestra Herramienta de selección de productos para limitar sus opciones


Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos



Loredana Moro et al.
The Journal of biological chemistry, 281(31), 22100-22107 (2006-06-07)
Aberrant interaction of carcinoma cells with basement membranes (BM) is a fundamental pathophysiological process that initiates a series of events resulting in cancer cell invasion and metastasis. In this report, we describe the results of our investigations pertaining to the
Jimmy M-M Kwok et al.
Molecular cancer research : MCR, 8(1), 24-34 (2010-01-14)
The transcription factor Forkhead box M1 (FOXM1) is a key regulator of cell proliferation and is overexpressed in many forms of primary cancers, leading to uncontrolled cell division and genomic instability. To address the role of FOXM1 in chemoresistance, we
Loredana Moro et al.
The Journal of biological chemistry, 280(23), 22482-22491 (2005-04-05)
BRCA2 is a tumor suppressor gene that when mutated confers an increased susceptibility to developing breast and prostate carcinoma. Besides its role in mediating DNA repair, new evidence suggests that BRCA2 may also play a role in suppressing cancer cell



Questions

Reviews

No rating value

Active Filters