95144

Retinol

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

• Sinónimos: Alcohol de vitamina A, Axerophthol, Vitamina A, Vitamina A₁, todo-trans-3,7-Dimetil-9-(2,6,6-trimetil-1-ciclohexen-1-il)-2,4,6,8-nonatetraen-1-ol
• Fórmula empírica (notación de Hill): C₂₀H₃₀O
• Número de CAS: 68-26-8
• Peso molecular: 286.45
• Beilstein: 403040
• Número CE: 200-683-7
• Número MDL: MFCD00001552
• Código UNSPSC: 12352205
• eCl@ss: 34058018
• ID de la sustancia en PubChem: 57653654
• NACRES: NA.28

Propiedades

• origen biológico: synthetic
• Línea del producto: BioXtra
• Análisis: ≥97.5% (HPLC)
• formulario: (Powder or Powder with Lumps)
• actividad específica: ~3100 U/mg
• caducidad: limited shelf life
• color: faint yellow to very dark yellow
• mp: 56-61 °C; 61-63 °C (lit.)
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
• InChI: 1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
• Clave InChI: FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Descripción

Descripción general

Retinol or vitamin A alcohol is the main circulating form of vitamin A.

Aplicación

Retinol has been used:

• as a standard in peak identification and quantification in reverse phase HPLC
• as a standard to estimate the concentration of vitamin A
• to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells
• as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay

Acciones bioquímicas o fisiológicas

It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid.

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Definición de unidad

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H317,H319,H360FD,H413
• Consejos de prudencia: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 1
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves