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T4512

(±)-Taxifolin hydrate

≥90% (HPLC)

Sinónimos:

3,3′,4′,5,7-Pentahydroxyflavanone hydrate, Dihydroquercetin hydrate

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Tamaño de envaseSKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
US$ 516,00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C15H12O7 · xH2O
Número CAS:
24198-97-8
Peso molecular:
304.25 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
24278739
UNSPSC Code:
12352200
MDL number:
MFCD11044454

US$ 516,00

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Quality Segment

100

assay

≥90% (HPLC)

form

powder

solubility

DMSO: 20 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI

1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1

InChI key

DNQPGSVMBPSRIR-LDXVYITESA-N

Gene Information

mouse ... Hexa(15211)

General description

Taxifolin or dihydroquercetin is a naturally occurring secondary metabolic compound[1] found in many plants such as onions, milk thistle, Douglas fir bark, and French maritime pine bark.[2]

Application

(±)-Taxifolin hydrate has been used to evaluate its effects when co-supplemented with trehalose to improve the quality of post-thawed ram semen.[3] It may have been used as a reference standard to analyze the bioactive components of ethanolic extract of P. orientale (POE) using high-performance liquid chromatography (HPLC).[4]

Biochem/physiol Actions

(±)-Taxifolin exerts various pharmacological properties that include anti-inflammatory, anti-cancer, antiviral,[1] and antimicrobial activities.[2] It displays neuroprotective, hepatoprotective effects, and it also protects against cardiovascular diseases.[2]
Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

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Este artículo
17793PHL89284580553
(±)-Taxifolin hydrate ≥90% (HPLC)

Sigma-Aldrich

T4512

(±)-Taxifolin hydrate

Quercetin 3-β-D-glucoside ≥90% (HPLC)

Sigma-Aldrich

17793

Quercetin 3-β-D-glucoside

(+)-Taxifolin phyproof® Reference Substance

PHL89284

(+)-Taxifolin

(±)-Taxifolin hydrate An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M⁻¹ s⁻¹) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

Sigma-Aldrich

580553

(±)-Taxifolin hydrate

form

powder

form

-

form

powder

form

solid

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥95.0% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL

solubility

-

solubility

-

solubility

ethanol: 20 mg/mL

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000562343
0000562343
0000402339
0000402339
0000238240

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Artículos

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Fatty Acid Synthesis in Cancer Cells

Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.

Contenido relacionado

Yung-Jia Chiu et al.
Journal of food and drug analysis, 26(1), 369-379 (2018-02-02)
Polygonum orientale L. (Polygonaceae) fruits have various medicinal uses, but their hepatoprotective effects have not yet been studied. This study investigated the hepatoprotective activity of the ethanolic extract of P. orientale (POE) fruits against carbon tetrachloride (CCl4)-induced acute liver injury
Christudas Sunil et al.
Phytochemistry, 166, 112066-112066 (2019-07-22)
Taxifolin (3,5,7,3,4-pentahydroxy flavanone or dihydroquercetin) is a flavonoid commonly found in onion, milk thistle, French maritime pine bark and Douglas fir bark. It is also used in various commercial preparations like Legalon™, Pycnogenol®, and Venoruton®. This review focuses on taxifolin's
Cong Cai et al.
Frontiers in pharmacology, 9, 1286-1286 (2018-11-30)
Osteoporosis is a highly prevalent disease which has been a major public health problem and considered to be associated with chronic low-grade systemic inflammation and oxidative damage. Taxifolin is a natural flavonoid and possesses many pharmacological activities including antioxidant and
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Número de artículo de comercio global

SKUGTIN
T4512-100MG04061833276334
T4512-25MG04061837346316

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