This product is soluble in water at 1mg/mL. Working aliquots may be stored at -20°C. Avoid repeated freeze/thaw cycles.
Long-term stability studies have not been performed. However, various sources state the this compound is stable in solution at 4°C several days and may be stored frozen for extended periods with the addition of a carrier protein (HSA or BSA) at 0.1%. This information has not been validated.
S1763
Somatostatin
powder, BioReagent, suitable for cell culture
Sinónimos:
Growth hormone release inhibiting factor, SRIF, Somatostatin-14, Somatotropin release inhibiting factor
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C76H104N18O19S2
Número CAS:
Peso molecular:
1637.88
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
EC Number:
254-186-5
Beilstein/REAXYS Number:
6436064
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥97% (HPLC)
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Servicio técnico
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Permítanos ayudarlebiological source
synthetic (organic)
Quality Level
product line
BioReagent
assay
≥97% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[H]N1[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(CO)C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C1=O)C(O)=O
InChI
1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57?,58-,59-,62-,63-/m0/s1
InChI key
NHXLMOGPVYXJNR-FQSIDJEASA-N
Gene Information
human ... SSTR1(6751), SSTR2(6752), SSTR3(6753), SSTR4(6754), SSTR5(6755)
Application
Somatostatin has been used in cell culture. It has also been used in the study of glucose-6-phosphate dehydrogenase activity in monolayer cultures of thyroid epithelial cells.
Biochem/physiol Actions
Somatostatin regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
Somatostatin (SST) is a peptide. It performs several functions like anti-proliferation, pro-apoptosis and anti-migration. Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3–5).
Somatostatin (SST) is a peptide. It performs several functions like anti-proliferation, pro-apoptosis and anti-migration. Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3–5).
Physical form
powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Preparation Note
To prepare 2 μg/ml stock solution, dissolve in 5 ml sterile culture medium per μg somatostatin.
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Este artículo | ||
|---|---|---|
| biological source synthetic (organic) | biological source - | biological source rabbit |
| assay ≥97% (HPLC) | assay ≥97% (HPLC) | assay - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 |
| product line BioReagent | product line - | product line - |
| form powder | form powder | form - |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) immunohistochemistry: suitable (paraffin) |
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Trace amine-associated receptor 1 localization at the apical plasma membrane domain of fisher rat thyroid epithelial cells is confined to cilia
Szumska, J, et al.
European thyroid journal, 4(Suppl. 1), 30-41 (2015)
Does somatostatin have a role in the regulation of cortisol secretion in primary pigmented nodular adrenocortical disease (ppnad)? a clinical and in vitro investigation.
Bram Z
The Journal of Clinical Endocrinology and Metabolism, 99(5), E891-E901 (2014)
SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males
Shen Z, et al.
Diagnostic Pathology, 11(1), 10-10 (2016)
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| S1763-.5MG | 04061832309378 |
| S1763-1MG | 04061836913816 |
| S1763-250UG | 04061832309392 |
| S1763-.1MG | 04061836913519 |
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こちらの製品を溶解後-20℃に凍結保存した場合、どれほどの期間安定（使用可能）か情報がございましたら教えてください。 よろしくお願いいたします。
1 answer-
Helpful?
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Do I need to filter it after reconstituting it in sterile water?
1 answer-
This is not a sterile powder. Stock solutions should be filter sterilized prior to use.
Helpful?
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Can I reconstitute Somatostatin in sterile water or PBS?
1 answer-
This product can be reconstituted in sterile water at 1mg/mL. While it is very likely soluble at this rate in PBS as well, we have not tested the product to confirm.
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