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Merck

M2140

Sigma-Aldrich

1-Decanoyl-rac-glycerol

≥99%

Sinónimos:

Monocaprin

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About This Item

Fórmula empírica (notación de Hill):
C13H26O4
Número de CAS:
Peso molecular:
246.34
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (organic)

assay

≥99%

form

powder

functional group

ketone

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(OCC(O)CO)CCCCCCCCC

InChI

1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3

InChI key

LKUNXBRZDFMZOK-UHFFFAOYSA-N

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Categorías relacionadas

Application


  • Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.: This research presents advanced assays for screening inhibitors of monoacylglycerol acyltransferase, with implications for metabolic disease treatment. 1-Decanoyl-rac-glycerol is a key compound in the study (Qi J et al., 2017).

  • Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.: The paper describes a novel surfactant system using 1-Decanoyl-rac-glycerol, which improves the NMR spectroscopy of proteins and nucleic acids, offering better resolution and reduced viscosity (Dodevski I et al., 2014).

Biochem/physiol Actions

Monocaprin (glycerol monocaprate) is used in the development of antimicrobial disinfectants active against enveloped viruses, and certain yeast and bacteria such as candida albicans and campylobacter.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Skuli Skulason et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 41(1), 61-67 (2011-05-04)
Current treatment of herpes labialis is usually with topical antiviral drugs and early drug administration is required for effectiveness. Monocaprin, a 1-monoglyceride of capric acid, has high microbicidal activity in vitro and efficiently inactivates herpes simplex virus. Tetracyclines are inhibitors
Thórunn O Thorgeirsdóttir et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(2), 333-342 (2005-01-22)
The purpose of this study was to characterize the rheological and structural properties of a pharmaceutical multicomponent hydrogel formulation. This formulation consists of a hydrogel-forming poly(acrylic acid) polymer (Carbopol 974P), microbicide (monocaprin), non-ionic surfactant (Tween 20 or Tween 40), and
P Reis et al.
Langmuir : the ACS journal of surfaces and colloids, 22(19), 8169-8177 (2006-09-06)
Starting from gold chips, we have tailor-made three surfaces by the self-assembly monolayer technique: one entirely hydrophobic, one hydrophobic with dispersed carboxyl groups, and one hydrophilic, containing hydroxyl groups. Rhizomucor miehei lipase has been adsorbed to the hydrophobic and the
Thórunn Osk Thorgeirsdóttir et al.
Acta odontologica Scandinavica, 64(1), 21-26 (2006-01-24)
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans. Solutions containing monocaprin were formulated and tested in vitro against a number of micro-organisms, including species found in the
Halldor Thormar et al.
Applied and environmental microbiology, 72(1), 522-526 (2006-01-05)
Of 11 fatty acids and monoglycerides tested against Campylobacter jejuni, the 1-monoglyceride of capric acid (monocaprin) was the most active in killing the bacterium. Various monocaprin-in-water emulsions were prepared which were stable after storage at room temperature for many months

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