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A9899

Antazoline hydrochloride

Name: Antazoline hydrochloride
Brand: SIGMA

Sinónimos:

2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride

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Acerca de este artículo

Fórmula empírica (notación de Hill):

C₁₇H₁₉N₃ · HCl

Número CAS:

2508-72-7

Peso molecular:

301.81

NACRES:

NA.77

PubChem Substance ID:

24277763

UNSPSC Code:

12352200

EC Number:

219-719-8

MDL number:

MFCD00058145

Form:

powder

Quality level:

200

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Propiedades

form

powder

Quality Level

200

originator

Novartis

SMILES string

Cl.C1CN=C(CN(Cc2ccccc2)c3ccccc3)N1

InChI

1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H

InChI key

SWKDMSRRIBZZAY-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

Descripción

Biochem/physiol Actions

Imidazoline agonist; H₁ histamine receptor antagonist.

Imidazoline agonist; more potent than efaroxan in inducing insulin release from β cells; H₁ histamine receptor antagonist.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Este artículo	D3630	A1210000	N5504
Sigma-Aldrich A9899 Antazoline hydrochloride	Sigma-Aldrich D3630 Diphenhydramine hydrochloride	A1210000 Antazoline hydrochloride	Sigma-Aldrich N5504 Naphazoline hydrochloride
form powder	form powder	form -	form powder
Quality Level 200	Quality Level 200	Quality Level -	Quality Level 100
originator Novartis	originator Johnson & Johnson	originator -	originator Allergan
Gene Information human ... HRH1(3269)	Gene Information human ... HRH1(3269)	Gene Information human ... HRH1(3269)	Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

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pictograms

GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H315,H319,H335

pcodes

P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor.

G Olmos et al.

British journal of pharmacology, 127(6), 1317-1326 (1999-08-24)

This study was designed to assess the potential neuroprotective effect of several imidazol(ine) drugs and agmatine on glutamate-induced necrosis and on apoptosis induced by low extracellular K+ in cultured cerebellar granule cells. Exposure (30 min) of energy deprived cells to

Demand for food and cocaine in Fischer and Lewis rats.

Chesley J Christensen et al.

Behavioral neuroscience, 123(1), 165-171 (2009-01-28)

Fischer and Lewis rat strains often serve as animal vulnerability models for drug abuse and addiction. When these strains respond for drugs of abuse, several measures, including total drug intake, response rate and progressive-ratio breakpoints, have been reported to be

Effects of imidazoline binding site ligands on the growth and viability of clonal pancreatic beta-cells.

M Mourtada et al.

Naunyn-Schmiedeberg's archives of pharmacology, 361(2), 146-154 (2000-02-24)

Pancreatic beta-cells express imidazoline binding sites which play a role in the regulation of insulin secretion, but it is not known whether ligands for these sites also affect other aspects of beta-cell physiology. In the present study, we have investigated

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Número de artículo de comercio global

SKU	GTIN
A9899-25G	04061832088778

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