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A165

Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt

Name: Rp-Adenosine 3&#8242;,5&#8242;-cyclic monophosphorothioate triethylammonium salt
Brand: SIGMA
Price: 246 USD

≥98% (HPLC), cAMP antagonist, powder

Sinónimos:

Rp-Cyclic 3′,5′-hydrogen phosphorothioate adenosine triethylammonium salt, Rp-cAMPS triethylammonium salt

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Tamaño de envase	Disponibilidad	Precio
1 mg	Comprobar disponibilidad del carrito	US$ 246,00
5 mg	Comprobar disponibilidad del carrito	US$ 1.020,00
10 mg	Comprobar disponibilidad del carrito	US$ 1.920,00

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₁₀H₁₁N₅O₅PS · C₆H₁₆N

Número CAS:

151837-09-1

Peso molecular:

446.46

UNSPSC Code:

41106305

PubChem Substance ID:

24890575

NACRES:

NA.77

MDL number:

MFCD03703495

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

desiccated

US$ 246,00

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Propiedades

Nombre del producto

Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt, powder, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H₂O: 10 mg/mL

λ_max

258 nm

storage temp.

−20°C

SMILES string

CCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=S)O[C@H]4[C@H]3O

InChI

1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21?;/m1./s1

InChI key

OXIPZMKSNMRTIV-NVGWRVNNSA-N

Descripción

Application

Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt has been used as an antagonist of cAMP to block the cAMP-PKA signal pathway.

Biochem/physiol Actions

Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt is capable of inhibiting protein kinase A (PKA).

Rp-Diastereomer of adenosine-3′,5′-cyclic monophosphothioate. Specific membrane-permeable inhibitor of activation by cAMP of cAMP-dependent protein kinase I and II; resistant toward cyclic nucleotide phosphodiesterases; blocks cAMP-mediated effects in numerous systems.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Extremely hygroscopic. Store desiccated.

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Este artículo	A166	B6684	A6885
Sigma-Aldrich A165 Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt	Sigma-Aldrich A166 Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate	Sigma-Aldrich B6684 Rp-8-Bromo-β-phenyl-1,N²-ethenoguanosine 3′,5′-cyclic monophosphorothioate sodium salt	Sigma-Aldrich A6885 Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98.0% (HPLC)
form powder	form solid	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
storage condition desiccated	storage condition -	storage condition -	storage condition -
solubility H₂O: 10 mg/mL	solubility H₂O: soluble	solubility H₂O: 15 mg/mL at ≤60 °C	solubility H₂O: 10 mg/mL

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number

0000414860

0000524809

0000414859

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Número de artículo de comercio global

SKU	GTIN
A165-1MG	04061833342626
A165-5MG	04061832895604
A165-10MG	04061832895598

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