77151
Pepsina from porcine gastric mucosa
powder, slightly beige, 1200-2400 U/mg
Sinónimos:
Pepsina A, Pepsina from hog stomach
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| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 1 g | Comprobar disponibilidad del carrito | US$ 112,00 | |
| 25 g | Comprobar disponibilidad del carrito | US$ 1.620,00 |
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Número CAS:
UNSPSC Code:
12352204
eCl@ss:
42010127
EC Number:
232-629-3
NACRES:
NA.54
MDL number:
Specific activity:
1200-2400 U/mg
US$ 112,00
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powder
specific activity
1200-2400 U/mg
mol wt
35 kDa
color
slightly beige
UniProt accession no.
storage temp.
2-8°C
Gene Information
pig ... LOC396892(396892)
Application
Puede utilizarse hidrólisis con pepsina para producir los fragmentos F(ab′)2 de los anticuerpos. pepsina en www.sigma-aldrich.com/enzymeexplorer
Biochem/physiol Actions
Escisión preferente: residuos hidrófobos y aromáticos en las posiciones P1 y P1′. Rompe los enlaces Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe y Phe-Tyr en la cadena β de la insulina
Analysis Note
pH óptimo es 2-4. Activa en urea 4 M y HCl de guanidina 3 M. Estable a 60 ºC. La pepsina se desactiva de manera irreversible a pH 8,0 - 8,5.
Other Notes
1 U corresponds to the amount of enzyme which increases the absorbance at 280 nm by 0.001 per minute at pH 2.0 and 37°C (Hemoglobin, Cat.No. 51290, as substrate) 15′000 absorbance-U as described above are equivalent to ∼1 Bergmeyer-U. 1 Bergmeyer-U is the amount of enzyme which hydrolyzes 1 μmol Acetyl-L-phenyl-3,5-diiodo-L-tyrosine at pH 2.0 and 37°C
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Este artículo | |||
|---|---|---|---|
| Gene Information pig ... LOC396892(396892) | Gene Information pig ... LOC396892(396892) | Gene Information pig ... LOC396892(396892) | Gene Information pig ... LOC396892(396892) |
| specific activity 1200-2400 U/mg | specific activity ≥3,200 units/mg protein | specific activity ≥2,500 units/mg protein (E1%/280) | specific activity - |
| form powder | form lyophilized powder | form lyophilized powder | form powder |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| mol wt 35 kDa | mol wt 35 kDa | mol wt 35 kDa | mol wt 35 kDa |
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signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| 77151-5G | 04061833627396 |