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46802

Sulfamethazine

Name: Sulfamethazine
Brand: SIAL
Price: 89.6 USD

VETRANAL^®, analytical standard

Sinónimos:

4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine

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Tamaño de envase	SKU	Disponibilidad	Precio
250 mg		Comprobar disponibilidad del carrito	US$ 89,60

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Fórmula empírica (notación de Hill):

C₁₂H₁₄N₄O₂S

Número CAS:

57-68-1

Peso molecular:

278.33

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757245

EC Number:

200-346-4

Beilstein/REAXYS Number:

261304

MDL number:

MFCD00006066

US$ 89,60

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Propiedades

grade

analytical standard

Quality Segment

200

agency

EPA 1694

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

clinical testing

format

neat

mode of action

DNA synthesis | interferes, enzyme | inhibits

SMILES string

Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI key

ASWVTGNCAZCNNR-UHFFFAOYSA-N

Descripción

General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo	S6256	S1900000	Y0001495
Supelco 46802 Sulfamethazine	Sigma-Aldrich S6256 Sulfamethazine	S1900000 Sulfadimidine	Y0001495 Sulfadimidine for peak identification
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -	technique(s) -
application(s) clinical testing	application(s) -	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
format neat	format -	format neat	format neat
Quality Level 200	Quality Level 200	Quality Level -	Quality Level -
grade analytical standard	grade -	grade pharmaceutical primary standard	grade pharmaceutical primary standard
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -	shelf life -

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

pictograms

GHS07

signalword

Warning

hcodes

H315

pcodes

P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364

Hazard Classifications

Skin Irrit. 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling.

Vincent Curtin et al.

Molecular pharmaceutics, 10(1), 386-396 (2012-11-29)

The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T(g)) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates whether coprocessing a model API, sulfadimidine (SDM)

Biodegradation of sulfamethazine by Trametes versicolor: Removal from sewage sludge and identification of intermediate products by UPLC-QqTOF-MS.

Ma Jesús García-Galán et al.

The Science of the total environment, 409(24), 5505-5512 (2011-09-29)

Degradation of the sulfonamide sulfamethazine (SMZ) by the white-rot fungus Trametes versicolor was assessed. Elimination was achieved to nearly undetectable levels after 20 h in liquid medium when SMZ was added at 9 mg L(-1). Experiments with purified laccase and

Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae.

M Rérat et al.

Preventive veterinary medicine, 103(4), 265-273 (2011-09-29)

The present study was conducted to evaluate the efficacy of two prophylactic antibiotic treatments against bovine respiratory disease (BRD) in veal calves. In addition, the antibiotic susceptibilities of isolated Pasteurellaceae were tested. The calves were treated either on the day

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Número de artículo de comercio global

SKU	GTIN
46802-250MG	04061835560752

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