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B1636
Pentagastrin
≥95% (HPLC), powder, CCK2 receptor agonist
Sinónimos:
Peptavlon, Petogasrin, N-t-Boc-β-Ala-Trp-Met-Asp-Phe amide
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| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 25 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 215,00 € | |
| 100 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 714,00 € |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C37H49N7O9S
Número CAS:
Peso molecular:
767.89
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
226-889-7
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality level:
Storage condition:
(Keep container tightly closed in a dry and well-ventilated place.)
215,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarleNombre del producto
Pentagastrin, ≥95% (HPLC), powder
Quality Level
assay
≥95% (HPLC)
form
powder
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
color
white to off-white
solubility
DMF: 20 mg/mL, clear, colorless to faint yellow or tan
storage temp.
−20°C
SMILES string
CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CCNC(=O)OC(C)(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc3ccccc3)C(N)=O
InChI
1S/C37H49N7O9S/c1-37(2,3)53-36(52)39-16-14-30(45)41-28(19-23-21-40-25-13-9-8-12-24(23)25)34(50)42-26(15-17-54-4)33(49)44-29(20-31(46)47)35(51)43-27(32(38)48)18-22-10-6-5-7-11-22/h5-13,21,26-29,40H,14-20H2,1-4H3,(H2,38,48)(H,39,52)(H,41,45)(H,42,50)(H,43,51)(H,44,49)(H,46,47)
InChI key
NEYNJQRKHLUJRU-UHFFFAOYSA-N
Gene Information
mouse ... Cckbr(12426)
rat ... Cckar(24889), Cckbr(25706)
General description
Research area: Immunology & cytokines
Application
Pentagastrin has been used to bidirectionally modulate lateral nucleus of the amygdala (LA) activity. It has also been used as a cholecystokinin-2 receptor (CCK2R) agonist to block the receptor binding for Ga-DOTA-MGS5 in AR42J rat pancreatic cell lines during cell uptake and receptor binding studies.[1]
Biochem/physiol Actions
Pentagastrin, a synthetic polypeptide is a gastrin analog. It contains the five C-terminal amino acids of gastrin. It acts as a cholecystokinin-2 (CCK2) receptor/ cholecystokinin-B (CCKB) receptor agonist.[2] Pentagastrin stimulates the secretion of pepsin and gastric acid. It also aids in the evaluation of gastric acid secretory function.[3] Pentagastrin exhibits panicogenic/ anxiogenic effects and thereby induces panic attacks in panic disorder (PD) patients.[2]
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Este artículo | |||
|---|---|---|---|
| form powder | form powder | form solid | form film |
| assay ≥95% (HPLC) | assay >90% (HPLC) | assay - | assay ≥95% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| storage condition (Keep container tightly closed in a dry and well-ventilated place.) | storage condition - | storage condition - | storage condition desiccated |
| solubility DMF: 20 mg/mL, clear, colorless to faint yellow or tan | solubility 1% ammonia: soluble 1 mg/mL, clear, yellow | solubility - | solubility - |
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Consistency of immigrant suicide rates in Austria with country-of-birth suicide rates: A role for genetic risk factors for suicide?
Voracek M, et al.
Psychiatry Research, 170(2-3), 286-289 (2009)
A Imdahl et al.
The Journal of surgical research, 86(1), 108-115 (1999-08-24)
To clarify the impact of the classic gastrin/CCK-B receptor on the growth of benign and malignant colonic cells, two permanent cell lines expressing this receptor have been established. The conditionally immortalized nonmalignant colonic cell line YAMC and the colonic carcinoma
Y Keto et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(2), 147-153 (2011-11-10)
Gastroduodenal acidification has been reported to aggravate upper abdominal discomfort and pain that are symptoms suffered by functional dyspepsia (FD) patients. Delayed gastric emptying and hypersensitivity to gastric distension (GD) contribute importantly to the pathophysiology of FD. In the present
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| B1636-25MG | 04061833426265 |
| B1636-100MG | 04061832674551 |
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What is the Department of Transportation shipping information for this product?
1 respuesta-
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How can Pentagastrin, Product B1636, solutions be stored?
1 respuesta-
Pentagastrin is subject to oxidation in solution. A pentagastrin solution in DMF can be stored frozen to protect the TRP and MET from oxidation. Further protection from oxidation can be insured if the solution is prepared with degassed solvent and the solution is stored under an inert gas such as argon or dry nitrogen gas.
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What is the shelf-life of Pentagastrin, Product B1636?
1 respuesta-
This product does not have any official shelf-life or expiration dating associated with it. The only date shown on the certificate of analysis will be the QC Release date. For customers whose systems require formal date management, use of a date one year from shipment is supported by our terms and conditions of supply.
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What is Pentagastrin, Product B1636, soluble in?
1 respuesta-
Pentagastrin is soluble in either dimethylformamide (DMF) or DMSO at a concentration of 20 mg/mL.
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