Saltar al contenido
Merck

B154

BU224 hydrochloride

solid

Sinónimos:

2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride

Slide 1 of 1
Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

En este momento no podemos mostrarle ni los precios ni la disponibilidad

Acerca de este artículo

Fórmula empírica (notación de Hill):
C12H11N3 · HCl
Peso molecular:
233.70
NACRES:
NA.77
PubChem Substance ID:
24277761
UNSPSC Code:
12352202
MDL number:
MFCD00467639
Form:
solid
Quality level:
200

Documentos clave

Ver Toda la documentación

Saltar a

Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

form

solid

Quality Level

200

color

white

solubility

ethanol: 1.2 mg/mL, H2O: >16 mg/mL, 0.1 M NaOH: 24 mg/mL, 0.1 M HCl: >30 mg/mL

SMILES string

Cl[H].C1CN=C(N1)c2ccc3ccccc3n2

InChI

1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H

InChI key

DDFHQXAQWZWRSQ-UHFFFAOYSA-N

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 4

Este artículo
B4311I2909A6566
BU224 hydrochloride solid

Sigma-Aldrich

B154

BU224 hydrochloride

BF-170 hydrochloride ≥98% (HPLC), solid

Sigma-Aldrich

B4311

BF-170 hydrochloride

Indoramin hydrochloride ≥98% (HPLC), solid

Sigma-Aldrich

I2909

Indoramin hydrochloride

2-Hydroxysaclofen ≥98% (TLC), solid

Sigma-Aldrich

A6566

2-Hydroxysaclofen

form

solid

form

solid

form

solid

form

solid

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

solubility

ethanol: 1.2 mg/mL, 0.1 M NaOH: 24 mg/mL, H2O: >16 mg/mL, 0.1 M HCl: >30 mg/mL

solubility

H2O: 10 mg/mL

solubility

DMSO: ~24 mg/mL, H2O: insoluble

solubility

H2O: 1 mg/mL, 0.1 M HCl: 1.2 mg/mL, methanol: 1.4 mg/mL, DMSO: 28 mg/mL, 0.1 M NaOH: 9.5 mg/mL

color

white

color

orange

color

white to off-white

color

white

Biochem/physiol Actions

I2 Imidazoline receptor antagonist.

Features and Benefits

This compound is featured on the Imidazoline Binding Sites page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Hygroscopic; store desiccated

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

A Diaz et al.
European journal of pharmacology, 333(1), 9-15 (1997-08-20)
In this electrophysiological study, the effect of BU-224 (2-(4,5-dihydroimidazol-2yl)-quinoline hydrochloride)), a novel high affinity imidazoline I2 receptor ligand, was tested on the responses of nociceptive neurones in the spinal dorsal horn. When applied spinally, akin to an intrathecal application (i.t.)
A L Hudson et al.
Annals of the New York Academy of Sciences, 881, 81-91 (1999-07-23)
Over several years our group has sought to synthesize and identify selective ligands for imidazoline (I) receptors, in particular the I2 binding site. As a consequence, [3H]2-(2-benzofuranyl)-2-imidazoline (2BFI) has proved extremely useful for binding and autoradiographic studies. More recently we
Kazunori Kawamura et al.
Nuclear medicine and biology, 45, 1-7 (2016-11-12)
A positron emission tomography (PET) probe with ultra-high specific radioactivity (SA) enables measuring high receptor specific binding in brain regions by avoiding mass effect of the PET probe itself. It has been reported that PET probe with ultra-high SA can
Laura Micheli et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(3), 1005-1015 (2020-06-24)
Anti-cancer therapy based on the repeated administration of oxaliplatin is limited by the development of a disabling neuropathic syndrome with detrimental effects on the patient's quality of life. The lack of effective pharmacological approaches calls for the identification of innovative
Nazanin Mirzaei et al.
British journal of pharmacology, 178(3), 654-671 (2020-11-04)
Activation of type 2 imidazoline receptors has been shown to exhibit neuroprotective properties including anti-apoptotic and anti-inflammatory effects, suggesting a potential therapeutic value in Alzheimer's disease (AD). Here, we explored the effects of the imidazoline-2 ligand BU224 in a model
Ver todos los artículos relacionados

Número de artículo de comercio global

SKUGTIN
B154-5MG04061832088808

Preguntas

Revisiones

Sin puntuación

Filtros activos

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico