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441R-1

NKX3.1 (EP356) Rabbit Monoclonal Primary Antibody

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1 mL
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129,00 €
0.1 mL
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Acerca de este artículo

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP356, monoclonal
Application:
IHC (p)
Citations:
3

129,00 €


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP356, monoclonal

description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (441R-17), bottle of 7.0 mL predilute (441R-18), vial of 0.1 mL concentrate (441R-14), vial of 0.5 mL concentrate (441R-15), vial of 1.0 mL concentrate (441R-16)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... NKX3-1(4824)

General description

NKX3.1 is a prostate-specific androgen-regulated homeobox gene located on chromosome8p.1-2 NKX3.1 expression is seen in benign and malignant prostate epithelium. NKX3.1is a sensitive and specific tissue marker that can be used to help identify prostateadenocarcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]
NKX3.1 Positive Control Slides, Product No. 441S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo
SAB1412056SAB1404130131R-2
biological source

rabbit

biological source

mouse

biological source

mouse

biological source

rabbit

antibody form

culture supernatant

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

culture supernatant

clone

EP356, monoclonal

clone

3C1, monoclonal

clone

3H6, monoclonal

clone

EP78, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

capture ELISA: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500


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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Lot/Batch Number

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Rebecca J Asch-Kendrick et al.
Journal of clinical pathology, 67(9), 768-771 (2014-07-06)
NKX3.1 is an androgen-regulated tumour suppressor gene that is downregulated in prostate carcinoma. Immunohistochemistry for NKX3.1 is primarily specific for prostatic-derived tumours and tissue but is reported in a small number of breast carcinomas. NKX3.1 is also shown to inhibit
Bora Gurel et al.
The American journal of surgical pathology, 34(8), 1097-1105 (2010-07-01)
NKX3.1 is a prostatic tumor suppressor gene located on chromosome 8p. Although most studies have shown that staining for NKX3.1 protein is positive in the majority of primary prostatic adenocarcinomas, it has been shown to be downregulated in many high-grade
Ai-Ying Chuang et al.
The American journal of surgical pathology, 31(8), 1246-1255 (2007-08-02)
The histologic distinction between high-grade prostate cancer and infiltrating high-grade urothelial cancer may be difficult, and has significant implications because each disease may be treated very differently (ie, hormone therapy for prostate cancer and chemotherapy for urothelial cancer). Immunohistochemistry of



Número de artículo de comercio global

SKUGTIN
441R-180841683122173
441R-160841683122159
441R-140841683122135
441R-16-RUO04061832282367
441R-150841683122142
441R-18-RUO04061832282398
441R-17-RUO04061836597849
441R-15-RUO04061836606664
441R-14-RUO04061832282336
441R-170841683122166

Preguntas

  1. Can 441R-17 be used for western blot?

    1 respuesta
    1. The IVD product is only optimized for use in IHC tissue samples, and it is not encouraged to use for western blot for this IVD product.

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