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131R-2

Sigma-Aldrich

CD31 (EP78) Rabbit Monoclonal Primary Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

EP78, monoclonal

descripción

(For In Vitro Diagnostic Use in Select Regions (See Chart))

formulario

buffered aqueous solution

reactividad de especies

human

envase

bottle of 1.0 mL predilute (131R-27)
bottle of 7.0 mL predilute (131R-28)
vial of 0.1 mL concentrate (131R-24)
vial of 0.5 mL concentrate (131R-25)
vial of 1.0 mL concentrate (131R-26)

fabricante / nombre comercial

Cell Marque™

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

Información sobre el gen

human ... PECAM1(5175)

Categorías relacionadas

Descripción general

CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Endothelial cells also express this marker; therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms.1-3 Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells.4 Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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F Alexander-Sefre et al.
Journal of clinical pathology, 56(10), 786-788 (2003-09-30)
Lymphovascular space invasion (LVSI) is an important step in the complex process of tumour metastasis. Various methods have been used in the past to improve the histological detection of LVSI. To develop a sensitive immunohistochemical method for the detection of
B R De Young et al.
American journal of clinical pathology, 110(3), 374-377 (1998-09-05)
CD31 is a specific and sensitive marker of endothelial differentiation. Previous reports have described its immunoreactivity in large series of soft tissue neoplasms, as well as its comparison with other available and commonly used endothelial markers. CD31 reactivity in carcinomas
D V Parums et al.
Journal of clinical pathology, 43(9), 752-757 (1990-09-01)
A new monoclonal antibody, JC70, raised against a membrane preparation from a spleen affected by hairy cell leukaemia, recognises a membrane bound glycoprotein identical with that of the CD31 group of monoclonal antibodies. The antibody stains a fixation resistant epitope
J U Alles et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(2), 209-214 (1986-02-01)
A new monoclonal antibody (moab BW 200) of IgG3 kappa-isotype was generated which recognizes an epitope located on an antigen molecule restricted to human neoplastic and non-neoplastic endothelial cells. The molecular weight of the antigen was determined using immunoprecipitation analysis

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