5.08160

DPDPE

• Sinónimos: DPDPE, δ Opioid Receptor Agonist, DPDPE
• Fórmula empírica (notación de Hill): C₃₀H₃₉N₅O₇S₂
• Número CAS: 88373-73-3
• Peso molecular: 645.79
• MDL number: MFCD00076430
• UNSPSC Code: 12352200
• NACRES: NA.77
• Form: solid
• Assay: ≥99% (HPLC)
• Solubility: water: 1 mg/mL
• Color: off-white

Propiedades

• assay: ≥99% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: off-white
• solubility: water: 1 mg/mL
• storage temp.: −20°C
• SMILES string: S1SC([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C1(C)C)C(=O)O)Cc3ccccc3)NC(=O)[C@@H](N)Cc2ccc(cc2)O)(C)C
• InChI: 1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
• InChI key: MCMMCRYPQBNCPH-WMIMKTLMSA-N

Descripción

General description

A potent agonist selective for δ opioid receptor (EC₅₀ = 5.2 nM). Exhibits anti-convulsant effects in vivo in rats, also used in nociceptive studies.

Biochem/physiol Actions

Primary Target
δ opioid receptor

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, C., 1997. J. Pharmacol. Exp. Ther.283, 1151.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.

Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable