5.08017

nor-Binaltorphimine Dihydrochloride

≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem

• Sinónimos: nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine
• Fórmula empírica (notación de Hill): C₄₀H₄₃N₃O₆ · 2HCl
• Número de CAS: 105618-26-6
• Peso molecular: 734.71
• Número MDL: MFCD00069374
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• product name: nor-Binaltorphimine Dihydrochloride,
• Análisis: ≥98% (HPLC)
• Nivel de calidad: 100
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: white to off-white
• solubilidad: water: 50 mM
• temp. de almacenamiento: −20°C
• InChI: 1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2
• Clave InChI: GYEXSFKLGQBRBJ-UHFFFAOYSA-N

Descripción

Descripción general

A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.

Acciones bioquímicas o fisiológicas

Primary Target
kappa opioid receptor

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Kishioka, S., et al. 2013. Neurosci. Letters.In press.

Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable