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04-290

Anti-EGFR (CT) Antibody, clone 13G8

clone 13G8, from mouse

Sinónimos:

ERBB, mENA, ERBB1

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Tamaño de envaseSKUDisponibilidadPrecio
100 μg
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384,00 €

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
13G8, monoclonal
Application:
ELISA, ICC, WB
Citations:
11

384,00 €


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

13G8, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®, Upstate®

technique(s)

ELISA: suitable, immunocytochemistry: suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)

General description

180 kDa

Immunogen

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C terminus in human EGFR

Application

Anti-EGFR (C-terminus) Antibody, clone 13G8 detects level of EGFR (C-terminus) & has been published & validated for use in ELISA, IC & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Recognizes C-terminus domain of EGF receptor (aa1165-1186)

Physical form

100 µg of purified mouse monoclonal IgG lyophilized in PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified
Subsequent thiophilic adsorption and size exclusion chromatography

Preparation Note

2 years at -20°C from date of shipment

Analysis Note

Control
Includes EGF treated Hep2G lysate as a positive control
Routinely evaluated by immunoblot.

Other Notes

Replaces: 04-337; 04-338

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este artículo
04-28304-28204-281
conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

-

clone

13G8, monoclonal

clone

12A3, monoclonal

clone

3F2, monoclonal

clone

5F10, monoclonal

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

species reactivity

mouse, human

species reactivity

human, mouse

species reactivity

mouse, human, canine, rat

species reactivity

human

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)

Gene Information

dog ... Egfr(404306)
human ... EGFR(1956)
mouse ... Egfr(13649)
rat ... Egf(25313)

Gene Information

human ... EGFR(1956)


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Clase de almacenamiento

10 - Combustible liquids



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Katsuyuki Hotta et al.
Oncology reports, 17(2), 313-317 (2007-01-05)
Despite its tremendous antitumor effect in a subset of patients with non-small cell lung cancer (NSCLC), the exact mechanism of gefitinib-induced cell death has not been fully determined. In this study, forms of cell death in various NSCLC cell lines
Xiaozhu Zhang et al.
Journal of medical genetics, 44(3), 166-172 (2006-12-13)
Frequent overexpression of epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) makes EGFR a new therapeutic target. Two specific EGFR tyrosine kinase inhibitors, gefitinib (ZD1839, Iressa) and erlotinib (OSI-774, Tarceva), have been developed and approved by the US
Francesca Walker et al.
Experimental cell research, 313(3), 511-526 (2006-12-13)
The site of action of growth factors on mammalian cell cycle has been assigned to the boundary between the G1 and S phases. We show here that Epidermal Growth Factor (EGF) is also required for mitosis. BaF/3 cells expressing the



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SKUGTIN
04-29004053252582738

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