Accéder au contenu
Merck

Passer à

39488

Pyrimidine nucleoside phosphorylase

recombinant, expressed in E. coli, ≥1300 U/mL

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

Changer de vue
ConditionnementRéférenceDisponibilitéPrix
1 mL
Vérifier la disponibilité des articles du panier
196.00 CHF
5 mL
Vérifier la disponibilité des articles du panier
764.00 CHF

A propos de cet article

Numéro CAS:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Numéro CE :
Specific activity:
≥1300 U/mL
Recombinant:
expressed in E. coli

196.00 CHF


Vérifier la disponibilité des articles du panier

Demander une commande groupée
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider


recombinant

expressed in E. coli

Quality Level

form

liquid

specific activity

≥1300 U/mL

relevant disease(s)

cancer

storage temp.

−20°C

Application

Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis[1]. PyNPase is used to study breast cancer, specifically its role in angiogenesis[1].

Biochem/physiol Actions

Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate[2]. PyNPase plays a significant role in breast cancer angiogenesis[1].

Other Notes

One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C

Comparer avec des articles similaires

Voir la comparaison complète

Montrer les différences

1 of 1

Cet article
N2415540221N3665
specific activity

≥1300 U/mL

specific activity

≥10 units/mg protein

specific activity

≥25 units/mg protein

specific activity

≥70 units/mg protein

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

liquid

form

lyophilized powder

form

liquid

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

relevant disease(s)

cancer

relevant disease(s)

-

relevant disease(s)

-

relevant disease(s)

-


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents



M J Pugmire et al.
Structure (London, England : 1993), 6(11), 1467-1479 (1998-11-18)
Pyrimidine nucleoside phosphorylase (PYNP) catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway. In lower organisms (e.g. Bacillus stearothermophilus) PYNP accepts both thymidine and uridine, whereas in mammalian and other higher organisms it is specific for thymidine
K Mimori et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 10(1), 111-113 (1999-03-17)
The clinical significance of pyrimidine nucleoside phosphorylase (PyNPase) activity in breast carcinomas has never been determined. In 41 cases of breast carcinoma, the enzyme activity of PyNPase was determined by the high performance liquid chromatography (HPLC) assay and its value
K Okuyama et al.
Bioscience, biotechnology, and biochemistry, 60(10), 1655-1659 (1996-10-01)
The pyrimidine nucleoside phosphorylase (Py-NPase) of Bacillus stearothermophilus TH 6-2 is a dimer of 46-kDa subunits and catalyzes the reversible phosphorolysis of uridine and thymidine. The gene encoding this pyrimidine nucleoside phosphorylase (pyn gene) has been cloned and sequenced from



Numéro d'article de commerce international

RéférenceGTIN
CDS003547-250MG04061828966479
39488-1ML04061838082428
39488-5ML04061838082435

Questions

Reviews

No rating value

Active Filters